My husband has had UC since January 1, 2001. about the day after he delivered his last Christmas rush package for UPS after a frenzied (Peak) season with plenty of stress. That began a 6 month bout with it. Then he got it so bad he was out of work for 2 years. On prednisone in heavy doses, in and out of the hospital (TRYING TO SAVE HIS COLON AT ALL COSTS). Finally, after being on the verge of having colon taken out he recovers quite well and goes back to work. One year symptom free on Azacol, etc. Then it comes back after taking Anti-biotics two times in a row - EEKSSS - don't use anti-biotics if you are in remission. At least not two sets close together.
Anyway it has been a year and a half since he last worked-he was on 60/80 mg of prednisone at one point. Took him quite awhile to come off of it. Then when he was all the way off the symptoms that the prednisone masked came back with a vengence and his bowel perforated!! Needless to say he has NO large intestine now. Prednisone - makes you ravenously hungry, lots of weight gain/puffiness in face, you can become moody, flaring quickly so warn your spouse and family. My husband has cataracts now from long-term use. Some of the not so fun stuff.
Oh did I mention his appendix had burst and was walled off by the colon while he was on Prednisone - MIND YOU this IS NOT a side affect of prednisone, just what happened to him.
I said all of that to say this!! We both feel that we wish he would have had his colon taken long ago and not fought so hard to keep it. He feels SO MUCH better and is only 2 1/2 months out from the complete Ileostomy surgery. The second surgery took place two weeks ago - a rectal resection to strip the rectum of any glands or things that could continue with colitis or get cancer. This surgery is no picnic but in the end when we have our LIFE back we will be thrilled and over joyed. The bag we can live with, no more 15 pills a day, no energy....
I know being pregnant is a different situation but for others this may be the answer.