We talk a lot about
the side effects of UC meds here, and it's important for us to be aware of the potential good and bad effects of our medications. It may be a fair trade-off for you, but just wanted to make sure that Avandia (and nicotine too, for that matter) is associated with a significantly increased risk of cardiovascular disease and heart attack.
And there are options other than 5-ASA's and Prednisone. Many people respond very well to immunosuppressants, for instance.
Good luck to you, whichever way you decide to go. Hope you're soon feeling better.