Just a few questions from a newbie..........

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to many questions
Regular Member

Date Joined Jun 2008
Total Posts : 23
   Posted 6/12/2008 8:33 PM (GMT -6)   
Hi, I saw my doc on monday and he told me that the 5-ASA's I am allergic to.  So on tuesday he did a colonoscopy(?) and when he finally got out of there he wanted to know what ****** off my colon.  He put me on PREDNISONE 30mg daily for maybe as long as 4 months.  Is there anything else out there for this?
Can anyone tell me what I am up against?  PLEASE?
Reason for edit:
I have taken a word out of your post as you are not allowed to use explicit language in the forums. We have minors who use the site and we have to be careful. Darren 

Post Edited By Moderator (djdaz_1985) : 6/13/2008 3:22:38 AM (GMT-6)

Veteran Member

Date Joined Jan 2006
Total Posts : 2408
   Posted 6/13/2008 4:21 AM (GMT -6)   

HI there and Welcome to Ulcerative Colitis,

Im not going to pretend to be an expert as I am just helping out but I have done a little research for you. (Anyone, please feel free to correct me if I am wrong here!)

5-ASA = Mesalazine = Anti-Inflammatory Drug. I dont know what you call it in the US as you use trade names and I am from the UK where we use generic names (Possibly Asacol or Ipocol) Are you allergic to that? Have you been using it and the doctor has taken you off? When you doctor said about something irritating your colon, my best guess is that it was either the result of the allergic reaction or a food type you are eating that your bowel does not like (Foods vary from person to person). Prednisone is a steroid used in the short term for UC but there are alternatives. Im not sure what they are (hopefully someone will rescue me here!) but I know they exist.

If you have any other questions, please ask. There is no such thing as a stupid question if you dont know the answer.


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Silent Lucidity
Veteran Member

Date Joined Nov 2007
Total Posts : 625
   Posted 6/13/2008 5:31 AM (GMT -6)   
If you can't take 5-ASA's you definitely need to be put on an immuno-suppressive drug.Generally speaking,Azathioprine would be the first one to try,and would hopefully do the trick.Steroids are used,as they usually induce a quick remission,but they aren't a maintenance drug,whereas Azathioprine is.

A maintenance drug,in case you are unaware,is a drug that will/should keep you in remission.I hope your GI is going to be putting you on something like this.UC'ers have more drug options than ever these days,don't let the 5-ASA intolerance worry you too much.However,there are different forms of 5-ASA that you may be able to tolerate.You need to let us know what you've tried so far.
Procto-Sigmoiditis dx 1995.First Colonoscopy in ten years,on 29th Feb 2008,revealed moderate to severe Pancolitis.
Current meds;200mg Azathioprine daily.Pentasa 2 x 500mg 4 x daily.
Got Ryche?

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 6/13/2008 7:53 AM (GMT -6)   
Welcome to HealingWell. Are you sure you're allergic to all 5-ASA's? Some who don't tolerate Asacol can use Colazal or Sulfasalazine as their maintenance drug. You need to be sure you truly can't tolerate any of these options before writing off 5-ASA's.

Silent Lucidity is absolutely right. Prednisone is a "quick hit" drug to induce remission, and should be started at a relatively high dose and tapered, discontinued within three months. Long-term Prednisone use can have some side effects that make the short-term effects such as moon face, weight gain, irritability and insomnia, seem like a walk in the park. If you truly cannot take any of the 5-ASA's, the normal next step would be an immunosuppressant such as Imuran (Azathioprine) or Mercaptopurine (6-MP.) These take two to six months to take full effect, so should be started at the same time as the Pred generally.

If immunosuppressants don't do the trick for you, there is a whole newer group of medications called the biologicals. These include Remicade and Humira, which have been extremely successful for many of us. So don't despair, there are still many treatment options available.

If you aren't already, you need to be on a good probiotic to help keep the "good" bacteria in your colon at a healthy level. This helps prevent infection from pathogenic or "bad" bacteria, and helps many of us to have better colon health. Commonly used probiotics around here are VSL#3 (quite expensive, but backed by research), Culturelle and Primadophilus Reuteri. Or you can visit your pharmacy or health food store and select from what they have. The most effective probiotics generally are refrigerated.

Finally, many of our members have discovered various alternative therapies that have helped them feel better. If you browse through the posts here, you'll find a lot of suggestions. Be aware that different things work for different people.

Good luck, and I hope you're feeling better soon.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Avascular necrosis in both shoulders is my "forever" gift from steroid therapy.
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
Co-Moderator UC Forum
Please remember to consult your health care provider when making health-related decisions.

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