I'm not sure about Lialda but I know that with Asacol which is a similiar form of Lialda that it's best taken with food to prevent it from damaging your stomach. I was on Asacol for many years and always took it on an empty stomach. After years of doing this, I think my stomach decided to call it quits and I now have acid reflux and/or gastritis. I have to take Prilosec now and I truly believe it was due to taking Asacol without food. But if you're in doubt, you can always ask your pharmacist.
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs), Hydrocortisone E's, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Allergies-Singulair
~Secondary Reynauds Syndrome-'04-Norvasc~Spinal Stenosis~Sacroiliitis-epidural injections
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