Posted 6/24/2008 2:40 PM (GMT -6)
Hi, Once you've been exposed to TB, you'll always be positive. They say that you should never get another PPD test again, but I've had 3-4 over my life.
Any immuno-suppressant drug may activate dormant TB. I'm no expert, but from what I understand, when you're healthy, you're immune system can isolate the TB and create a hard outer shell around it. Immuno-suppressant drugs can deteriorate that shell and the TB can get out, making it active.
My previous GI put me on prednisone knowing full well that I have a pos. ppd. In fact, she told me not to take the other drugs like remicade. Then when I switched GI's, the new one was surprised and said that I shouldn't have taken the pred and that it could have activated the TB. The new doc also specializes in immunology, so I definately trust her about this.
Not sure about the 6mmp, but it would make sense with my limited knowledge.
piper_chris, it sounds like your ppd was negative, since it was non-reactive. I hope so. Also, I'm not sure about whether pred messes up the accuracy of the ppd test.
I posted this not to cause anyone excess worry, but because I thought it may be important info for some of us. Knowledge is power.