I agree....rectal meds are a life saver for me. I am also taking bee propolis, fish oil, mucosaheal and a calcium supplement. I have tried acupuncture, I can't really tell a difference with it. I am now trying a shake in place of breakfast called absorb plus. I have been keeping a log of my symptoms as well. I, like your wife developed UC at 19. Mine is directly linked to my hormones.....when they flucuate, I get UC symptoms. Keeping a log or journal may help you keep track of what foods set her off and if it is at all related to hormones. It can help with what meds/supplements are working for her too. There is a great log book at whole foods called body minder, that is the one I use and I think it helps a ton. Good luck to you and your wife....I know it means the world to her to have your support through this.