How nice that you are reaching out to try and help your wife. First, if she is not seeing a GI she should be. Managing UC with prednisone is not recommended. That drug has a long list of long term side effects that should be avoided. If she has been taking prednisone since age 19 she really needs to find a doctor who will help her get off of that drug. There are other drugs available to help gain remission. I would also suggest you get your wife involved in this board or in your local CCFA meetings. She needs to get educated about the disease since it is a chronic life-long disease. Meeting others with the disease can be very rewarding and helpful.
dx proctitis in 1987
dx UC in 1991, was stable until 1998
1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics
2000 lost all my B-12 stores and became anemic
2001 opted for j-pouch surgery- now living life med-free