Article: IBD flare-up during pregnancy raises preterm delivery risk

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dakotagirl
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Date Joined Apr 2006
Total Posts : 3402
   Posted 6/25/2008 7:13 AM (GMT -7)   

bookworm21
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Date Joined Mar 2008
Total Posts : 1766
   Posted 6/25/2008 7:21 AM (GMT -7)   
I wonder how many women who were in remission before getting pregnant flare-up during pregnancy.
Female, Age 19, Dx w/ UC August 2007
9 Asacol, Rowasa1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis), 1 Florastor, 50 mg 6MP,1 Primadophilus reuteri, 1 DanActive, Remicade (1st infusion 06/08), 2.4 g Lialda


ediekristen
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Date Joined Apr 2007
Total Posts : 1366
   Posted 6/25/2008 9:25 AM (GMT -7)   
Supposedly, for most women if you are in remission when you get pregnant you are likely to stay that way, and if you are flaring you are likely to continue flaring and even get worse.
Female, 22, Ulcerative colitis (pancolitis) since 1999; GERD; gastritis; osteopenia in hip & lumbar region of the spine from long term prednisone use.

Current Meds:
10mg Lexapro (for depression/social anxiety)
Digestive Advantage: Crohn's and Colitis formula (2 pills per day, started 5/14/08)
125mg Azathioprine
4800mg Asacol (Four 400mg tablets, three times a day)
 
 
 


LilyPirker
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Date Joined Jun 2008
Total Posts : 19
   Posted 6/25/2008 9:39 AM (GMT -7)   
I was in remission before I got pregnant and was fine until the third month and then starting flaring. I am six months now and have been flaring steadily since. It's not a really bad flare up but a nuisance nonetheless. My family doctor, OBGYN, and Gastro all tell me that I am having a healthy preganancy and the baby is doing just fine. I am hopeful that is the way it will continue and hope everything turns out fine in the end. As for the stats of women flaring during pregnancy, the rule of thumb tends to be a 1/3 stay the same, 1/3 get worse, and a 1/3 actually get better....some of us are just lucky and become that 1/3 that get worse! The important thing to note is making sure you are in remission when actually getting pregnant.

Diagnosed with UC in 2000

Medications:  Asacol 800mg tablets 5/day, Salofalk enema nightly


kb5
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Date Joined Jan 2007
Total Posts : 1015
   Posted 6/25/2008 9:52 AM (GMT -7)   
I learned at a seminar the rule of 1/3 as well.

They say that during pregnancy 1/3 of women flare, 1/3 get better, and 1/3 stay the same.

There was also a theory about the genetics involved. She said that if the baby is genetically like you, you are more likely to flare. But if the baby is genetically more like it's father than your body will see it as a foriegn entity and protect your body and you won't flare. This was a theory. Not sure if I believe it but it is an interesting idea.
Kelly, 30

Left sided UC diagnosed 1/98 age 19, Pan colitis diagnosed 1/07
Currently on 4x3 Asacol, no more pred after two years!!!! Off imuran as remicade is working!
Prontonix once daily for acid reflux, zofran 8mg every six hours for nausea
Remicade started 3/1/08...just had 4th infusion


shannon1
Regular Member


Date Joined Feb 2005
Total Posts : 369
   Posted 6/28/2008 2:02 PM (GMT -7)   
thanks for the article! It is important for women w/ IBD to take pregnancy and flares very seriously. I delivered both babies premature. First one delivered at 33wks, when i was in the throws of my first ever UC flare, that was undiagnosed at the time. Second child delivered at 34wks, flare began at conception after over a yr of remission.

side note, i do also have other maternal illness, so it was not determined for sure that the flare caused the preterm births.
2003, dx moderate UC
2000, dx selective IGA deficiency w/ anti IGA antibodies
2000, dx Antipholipid Antibody Syndrome
1999-current, chronic hemmoragic ovarian cysts, w/ partial ovary removal
1977, complete reconstruction of foot after lawnmower accident (chronic pain)
 
Meds
6mp 75mg, prednisone 40mg (just starting meds again)
percocet 5mg 3x day
potassium 3x day
 


dreamland
New Member


Date Joined Apr 2007
Total Posts : 19
   Posted 6/28/2008 6:00 PM (GMT -7)   
I'm 3 months pregnant right now and have been flaring the whole time. Actually, the only time I haven't been flaring since I was diagnosed in Feb of 2006, was during one of my prednisone treatments. I was on Imuran up until I found out I was pregnant, but stopped taking it on the advice of my baby doc. Switched back from Sulfasalazine to Asacol also. I've pretty much given up hope of ever going into remission at this point, and I worry about the effect all this is going to have on my baby. But what can I do? I'm trying to stay positive!
Diagnosed w/ uc in April of 2006.
Sulfasalazine 1000mg 4 times per day;
Protonix 40mg per day;
Zoloft 100mg per day;
Prenatal vitamin, folic acid


AMK77
Veteran Member


Date Joined Mar 2008
Total Posts : 678
   Posted 6/28/2008 8:02 PM (GMT -7)   
I'm currently 3 months pg. I'm hoping that I fall into the category of the 1/3 of women that get better. So far my UC has stayed the same or maybe has slightly improved. Fingers crossed! When I told my OB about my UC she didn't seem concerned at all, she said it didn't put me at a higher risk category so that made me feel a lot better.

Dreamland - when are you due? I'm due 1/16/09
31 yr old female, currently pregnant.
Diagnosed 2/29/08 with Mild Universal UC
I've had UC since 2000 but was in remission for most of those 8 years med free
Lialda Colazal & Asacol made symptoms worse, MUCH worse
Not taking any more meds for now. Trying a holistic approach.


dreamland
New Member


Date Joined Apr 2007
Total Posts : 19
   Posted 6/28/2008 10:16 PM (GMT -7)   
I'm due Dec 27th. It's been a difficult pregnancy for the most part, (gestational diabetes and a subchorionic tear, spotting) but now that i'm into my second trimester, things are looking up! How is your pregnancy going for you? Is this your first? This is my fourth!
Diagnosed w/ uc in April of 2006.
Asacol 4 tabs 3 times per day;
Protonix 40mg per day; Prometrium 200mg per day;
Zoloft 100mg per day; postassium tabs twice per day;
Prenatal vitamin; folic acid; Expecta DHA supplement


AMK77
Veteran Member


Date Joined Mar 2008
Total Posts : 678
   Posted 6/29/2008 6:34 AM (GMT -7)   
This is my 2nd pregnancy. I had morning sickness that has thankfully lessened in the last week. I have found that I have been a lot less paranoid this time around, even with UC, which has been nice. You have gone through so much already - I hope you feel better soon!
31 yr old female, currently pregnant.
Diagnosed 2/29/08 with Mild Universal UC
I've had UC since 2000 but was in remission for most of those 8 years med free
Lialda Colazal & Asacol made symptoms worse, MUCH worse
Not taking any more meds for now. Trying a holistic approach.

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