Lialda and flare up?

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Regular Member

Date Joined Feb 2008
Total Posts : 46
   Posted 6/26/2008 11:09 PM (GMT -6)   
I was switched from 9 Asacol daily to 2 Lialda a day a few weeks ago.  I read in previous threads that a few people were on it.  My doc said it was just like Asacol only i take less pills.  And from what i read from others comments it didn't seem like everyone was told that.  So i wanted to know a little more of what other people were told or read about it.  I only did a few basic things to look it up, i have not had the time to really look into it yet.
I am also starting a flare i think.  When i went to the doc i was seeing blood only in a few stolls during the week, and now it seems like a daily thing and some urgency is coming back as well.  The doc said its prob just a hemorid.  but i don't feel like it is, thats how my UC went un treated for about 5 months (diffrent doc) but i have a colonoscapy to check things out on Thursday next week so i guess nothing i can really do until then.  Remicade is the next step if i need it..
And i thought things were going so well!! i was feeling great.. starting to try and work of those roid pounds and loosing the moon face. But now i'm moody again (everytime i see blood or look in a mirror i get so disscoraged) I just don't know what to do.  (there needs to be a spell check on this, sorry my spelling is not the greatest)
20 year old college student, dx december 2006
meds: Asacol 400mg 4 pills 3x a day; protonix; prednisone (tapper, down from 40mg started 1/1/08) Lialda 2 pills a day; 6-mp 75 mg; iron supplament; one-a-day;
low residue diet

Regular Member

Date Joined Mar 2008
Total Posts : 68
   Posted 6/27/2008 8:44 AM (GMT -6)   

I started out with my Dr giving 1 Lialda a day and then because I was flaring so badly, he gave me 4 pills a day.  It is the same formulation as asacol, mesalamine.  The Lialda isn't really working for me though (asacol didn't either) so I am on Remicade now.  I still take 2 Lialda a day now because my Dr. says it can help prevent colon cancer.  Hope this helps.  I guess you'll know more about what's going on with you after your colonoscopy!  Maybe someone with more knowledge on the subject will chime in!


Regular Member

Date Joined May 2007
Total Posts : 169
   Posted 6/27/2008 9:30 AM (GMT -6)   
I was taking 4 Lialda a day for a while. I think it was causing diarrhea. It sure wasn't helping.
UC diagnosed Dec. 2006
Azathioprine 200mg/day
Prednisone 0 ! (After nearly 1 year)
Multivitamin, B complex vit., fish oil, fiber supplement, Nature's Way Primadophilus Optima, Digestive Advantage Crohn's & Colitis

Mommy pooh
Regular Member

Date Joined Apr 2008
Total Posts : 131
   Posted 6/27/2008 10:30 AM (GMT -6)   
I started on 2 Lialda for 4 weeks and thought things were a tiny bit better so my doctor increased my dose to 4 Lialda. He also increased my 6MP from 50mg to 75mg (after 15 weeks of no improvement in my flare on 50 mg). Within 3 days I was only having 2-3 BMs. That was about a week ago. Now I am having 1-2 BMs a day all formed and only tiny spots of blood on the pooh. I am VERY encouraged and hopeful that my flare may finally be coming to an end!! I think it was the Lialda because I was figuring that the increase in 6MP would need time to kick in just like when you start 6MP. I am going to do a Prometheus test in 2 weeks to make sure everything is ok with the 75mg dose of 6MP.
  • 25 years old
  • Ulcerative Colitis since Sept. 2004
    • 1st flare Sept-Nov 2004
    • 2nd flare Aug. 2007-present
  • Currently taking 1000mg Dipentum, 75mg 6MP, and weaning off Entocort at 6mg, 4 Lialda, Digestive Advantage Chrons/Colitis, and Women's One a Day


Veteran Member

Date Joined Mar 2008
Total Posts : 1580
   Posted 6/27/2008 10:36 AM (GMT -6)   
Had the same issue going from Asacol to Lialda...I up'd the Lialda to 4 per day and my rowasa's to every night for a week or so and now I'm down to 3 lialda and rowasa evry other night.

New Member

Date Joined Jun 2008
Total Posts : 10
   Posted 6/30/2008 1:50 PM (GMT -6)   
I am going through a flare at the current time and my current doctor placed me on 4 Lialda per day. I was on remission for almost 7 years with Asulfidine. I have gone via the Prednisone and have moved to the 6-mp while still on the Lialda. Dr. says that the Lialda doesn't always get you into remission but it works once in remission.

To be honest I am not a big fan Lialda because it does not seem to be doing it's job. That doesn't mean that it will not work for you.
Age: 39
Diagnosed UC: Dec 1999
Remission Cocktail: Azulfidine, Prednisone, Paragoric Liquid
UC Flare: March 2008
Current Meds: 4 Lialda, 2 Purinethol, 5 mg Prednisone (tapering)
Other ailments: HBP, Gout

Regular Member

Date Joined Jul 2006
Total Posts : 320
   Posted 6/30/2008 5:50 PM (GMT -6)   
I tried Lialda, what a nightmare! I was in a went straight downhill from there. Ended up in emergency thought I was having a heart attack. Turns out I was really dehydrated from losing so much blood and fluids.

Dx'D in 1990. Remission 1991 - 1/2005
Both flares were in extremely stressful times in my life
Colonoscopy 10/2005 80% of Colon diseased, or as I like to say "Intestinely challenged"
*****9/2007 dumped my GI who I refer to as "Satan" New GI, new med TOTAL remission with in 2 weeks.
Colazal 9 capsules a day*****

Regular Member

Date Joined Mar 2008
Total Posts : 212
   Posted 6/30/2008 7:56 PM (GMT -6)   
Lialda didn't work for me. I was taking 4 a day. It did give me the most horrendous gas I have ever had! But for other folks, it seems to work fine.

Just goes to show you how each one of us is so different.
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