I'm taking the same suppositories, but I've only been told to lay down for 30 minutes. My dosage is less than yours, so that may be why you have to lay down longer but three hours sounds like an eternity. Have you double-checked that with your doctor? I can't imagine anyone being expected to do that.
Ulcerative Proctitis - Diagnosed by colonoscopy January '08
Rowasa (Mesalamine) 60 ML 2X daily
Cortenama (Hydrocortisone) 100 ML 1X daily
Tried Canasa suppositories, Cortifoam, Prednisone, Colazal, Disgestive Advantage (Colitis), Fish Oil, Vitamins