switching asa'a?

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Eva Lou
Veteran Member


Date Joined Sep 2006
Total Posts : 3442
   Posted 7/2/2008 6:18 PM (GMT -6)   
hi people! I am thinking of swapping my Asacol to give Lialda a try- have been on Asacol since initial diagnosis- swore it wasn't doing anything (this was in '06), went off it, went into horrible year + flare, just now coming into some semblance of remission. I think. Anyway- clearly the Asacol is helping- have been back on since Fall of '06. I'm worried though- has anyone ever switched to a different asa & then gone into a fairly bad flare? One requiring steroids? I'm at the end of the med rops, so to speak, & I'm afraid if I switch things around, & something goes wrong... well then what do I do? I know some people have done better on Lialda then on Asacol- have any of you done worse?
diagnosed with UC '02
meds-
Asacol- 8 tabs/day
Remicade-10mgs/kg- since 4/07
Imuran- 100mgs/day
Culturelle
 
 
 
 


jujub
Elite Member


Date Joined Mar 2003
Total Posts : 10407
   Posted 7/2/2008 6:39 PM (GMT -6)   
My own personal philosophy is not to change anything if things are going well for me.
Judy
 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Avascular necrosis in both shoulders is my "forever" gift from steroid therapy.
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
 
Co-Moderator UC Forum
Please remember to consult your health care provider when making health-related decisions.


Eva Lou
Veteran Member


Date Joined Sep 2006
Total Posts : 3442
   Posted 7/2/2008 6:45 PM (GMT -6)   
yah, mine too! But I can't help but think "What if the Lialda works better?". I don't really see how the ASA's differ from one another- people claim they target different areas of the colon- doctos disagree. Where do you find this info, comparing asa's? All the stuff I read basically says they're all the same, just different doseages, manufacturers, etc.

diagnosed with UC '02
meds-
Asacol- 8 tabs/day
Remicade-10mgs/kg- since 4/07
Imuran- 100mgs/day
Culturelle
 
 
 
 


Red_34
Elite Member


Date Joined Apr 2004
Total Posts : 23551
   Posted 7/3/2008 1:00 PM (GMT -6)   
I couldn't find that much info about where which drug releases better and where but I did find this which is a good description:

http://www.medicinenet.com/ulcerative_colitis/page5.htm
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs), Hydrocortisone E's, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Allergies-Singulair, Allegra
~Secondary Reynauds Syndrome-'04-Norvasc~Spinal Stenosis~Sacroiliitis-epidural injections~bulging discs C5,C6&C7(?)~waiting for epidural injections
To help Healingwell - click here: DONATE
 
 
 
 

 
 


Eva Lou
Veteran Member


Date Joined Sep 2006
Total Posts : 3442
   Posted 7/3/2008 3:22 PM (GMT -6)   
thanks for the link! I'm still a little leery about switching, & not sure if I want to try it. My GI swears all asa's are the same. And on the drup webpages, they don't claim to be any different from any other asa's. Who knows!

PS- http://www.medscape.com/viewarticle/544678

While doing my own digging, I came across this study- once you get past the case study, it's good as far as comparing the 5asa's. They do say repeatedly that there is no significant difference between the asa's- that's what I've found in all the stuff I've come up with on the 'net.


diagnosed with UC '02
meds-
Asacol- 8 tabs/day
Remicade-10mgs/kg- since 4/07
Imuran- 100mgs/day
Culturelle
 
 
 
 

Post Edited (Eva Lou) : 7/3/2008 3:13:24 PM (GMT-6)


bap06
Regular Member


Date Joined Jun 2008
Total Posts : 57
   Posted 7/3/2008 9:04 PM (GMT -6)   
Hi - just recently (in the past couple of weeks) switched from Asacol to Lialda. Asacol was working fine, but wasn't seeming to keep me in remission for long, so my GI figured it was worth a try. I actually have been feeling a little better, but I don't know how much of that is just coincidence or in my head. But, I haven't noticed any bad effects either (yet). It is nice taking fewer pills!
*Diagnosed 10/07 (6 months pregnant w/ 2nd baby)
*Asacol (4 pills 3x a day)
Canasa
Prilosec
Calcium, multivitamin, Metamucil


bookworm21
Veteran Member


Date Joined Mar 2008
Total Posts : 1766
   Posted 7/5/2008 10:54 AM (GMT -6)   
I switched from Asacol to Lialda a few weeks ago, and there seems to be no difference between the two. But it is pretty awesome to only take meds one time per day!
Female, Age 19, Dx w/ UC August 2007
9 Asacol, Rowasa1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis), 1 Florastor, 50 mg 6MP,1 Primadophilus reuteri, 1 DanActive, Remicade (2nd infusion 06/26/08), 2.4 g Lialda
*exploring the option of surgery
 


TraciZ
Regular Member


Date Joined Aug 2007
Total Posts : 255
   Posted 7/5/2008 6:53 PM (GMT -6)   
I was on lialda from sept to april or march. It didn't work for me. Now, I've been taking asacol for about a month and think i'm in remission. the blood is almost gone and i'm feeling a lot better. we'll find out on wed when i have my colonoscopy. anyway, i think the asacol saved me from pred and remicade.

I agree with Judy- don't fix what's not broken.
Tressa 35 (F)
probably pancolitis
Colazal 3X3/day, Lialda upped to 4/day,Phosphatidylcholine 4 (420 mg capsules) once/day
Colazal 3X3/day (not generic)
Rowasa & Canasa as needed
Asacol 12/day

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