How long for Pred to work?

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Veteran Member

Date Joined Jul 2008
Total Posts : 823
   Posted 7/10/2008 6:57 AM (GMT -7)   
Hi - I have been basically having a 6 month flare with lots of bleeding.  My doctor is very conservative and he FINALLY prescribed 20 MG of Pred for four weeks...then I will start to taper off...I have never been on Pred before.  I have been taking it for 10 days so far and have seen quite a bit of improvement.  I am not completely clear though and am still have some slight bleeding and daily passing of mucus. 
How long does it usually take for the Pred to really work?  I don't know if I should call and ask the doctor to increase my dosage or if I should give it another week or so...any feedback from this group would be so welcome!  Thanks!

Regular Member

Date Joined May 2008
Total Posts : 61
   Posted 7/10/2008 12:42 PM (GMT -7)   


I posted a question about Pred earlier and there is alot of good information from people who have experience with it.  It is entitled "I have a stupid question about Pred"

I was on 40 mgs of Pred for two weeks and noticed a slight improvement.  My symptoms weren't all that severe to begin with, however.  I had some blood and no diarrhea.

Anyway, I would say call your doc.  If it concerns you, it should concern him/her.

Like I said, there is some really good information in my previous post.

Good Luck,


40 mgs of Pred
50 mgs of Imuran
3 Lialda
1 Canasa at night

Regular Member

Date Joined Jun 2008
Total Posts : 32
   Posted 7/12/2008 9:35 PM (GMT -7)   
i think you should ask to have your dose increase a little bit and then tapper off of that. I usually up my dose to 40mg when i'm flaring and it helped almost always.
Diagnosed with Severe Ulcerative Colitis in Dec 2005 at age 19
2nd flare up-Hospitalized for 41 days (april-may 2008)
prednisone 25mg (tapering)-taking sicne 2005 :(
asacol 400mg-9 pills a day
remicade (just started)
iron, calcium, vitamin c
Attempting Diet-Eat right for your blood type (Type O)

Regular Member

Date Joined Jul 2008
Total Posts : 100
   Posted 7/20/2008 12:09 AM (GMT -7)   
I started with 20 but it never worked. When I moved to 40 it worked and I eventually tappered off and was in remission for about two years. I just started back on the prednisone again on 40 I have only been on a week so not much improvement yet. It is a double edged sword. I don't sleep and feel jittery all day.
Prednisone 40mg a day
Asacol 400mg 4 pills 3 times a day

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