It's strongly suspected that long-term use of 5-ASA ..not only Asacol...helps reduce the risk of cancer in UC patients.
Since UC starts at the rectum it'd be a good plus for the use of rectal meds rather than assuming it's just the oral 5ASA meds.
At the 18 year mark, all my biopsies were A++....unremarkable, which is actually a good thing. I also have primary sclerosing cholangitis (PSC) which increases my colon/liver cancer risk over and above just having UC.
I attribute my current state in (a large) part to faithful use of the 5ASA meds to treat flares and for maintenance since diagnosis over 19 years ago and heading into year 20, and there would be no reason for my doc to suggest surgery just in case unless biopsies stated so.
I also attribute the slow progression of PSC to keeping my colon nice and quiet as continually as possible.
I've only had c-scopes about
every 3 years.
If a patient has chronic inflammation (with or without symptoms because not all show symptoms equalling the inflammation), I can see cancer risk increased just based on that fact. If one can use them, I would see it as some insurance.
For some UCers, 5-ASA isn't a possibility because of allergies and extreme side effects.
*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg; Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!