Colocort enemas

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Regular Member

Date Joined Jun 2008
Total Posts : 80
   Posted 7/23/2008 10:32 AM (GMT -6)   
I was wondering if anyone has had experience with these enemas.  I am currently almost through a 2 week course.  ASA meds make me worse off, and since pred was the usual savior.  The question I have is how much of the enema is absorbed by the body?  I feel like I am experiencing the same side effects of the oral Pred....yes I do feel they are helping, but I am wondering about the side effects and if I am just really back on pred again even though in enema form.  I was down to 2mg Pred and tapering when I started this and relatively stable...some good days and a few bad ones, but definately tollerable.  If I stop using these abruptly I am concerned I will crash like coming off of Pred without tapering.

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 7/23/2008 10:37 AM (GMT -6)   
With enemas it's always best to taper no matter what the docs say. Especially with any sort of steroid based med. I have been on and off Colocorts for 2 years - 1 year of almost constant use. Yes they can cause steroid type side effects but not nearly as strong as the oral. Only about 5-8mgs of steroid actually enters your bloodstream. Though I think that if you already have steroid in your body that it may make the side effects show up quicker. I know that was the case with me. After going off them and a month or so goes by and I have to start them up again, it's like I never stopped. The side effects hit me full force within a few days of starting them again.

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Regular Member

Date Joined Apr 2006
Total Posts : 171
   Posted 7/23/2008 3:20 PM (GMT -6)   
I have used colocort for years on and off. Yes, you can get pred side effects, but much less is absorbed by the body. I agree with Sherry to taper off. I also don't listen to my doctor and use them for shorter periods of time than suggested, but tapering off when I do. I have also found that when in remission, if I have any symptoms at all, I can use an enema once a week for a while and the symptoms go away. I am hesitant to suggest ignoring doctor's instructions, but I know what works for me.

And - welcome to HealingWell.

Diagnosed UC 1975. 
Azulfidine Entabs 500 mg. 4 twice a day
Azathioprine 100 mg per day
Colocort - as needed
Folic acid, vitamins C and D, multivitamin, metamucil, fish oil, turmeric 
Hospitalized 1997 - intravenous cyclosporine.

Regular Member

Date Joined Oct 2007
Total Posts : 348
   Posted 7/23/2008 8:35 PM (GMT -6)   
Definitely taper them for sure. I've never really noticed any side effects from them, just from the oral pred.
diagnosed with uc 27 years ago.  Enojoyed 20 year remission with just minor blips here and there (approximately 16 of those years without any meds)
In a flare for 2 very long years which Asacol didn't help at all.  Finally in remission again since Jan 2008, can't believe it..............
currently on Sulfasalazine 2 tabs 3x day. Folic acid, mesalamine enema once a week. Omega 3, Probiotics, multi vitamin, calcium supplement, Biotin 5000mcg, Fibercon.

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