Old Hat said...
The generic name of Colazal is basalazide disodium, but it breaks down to mesalamine inside the colon. That is a different dispersal than Asacol, which starts dissolving in the terminal ileum, according to recent clinical studies. Therefore, many gastros who keep up with UC research now think that Colazal is more effective in treating left-sided inflammation than other oral 5-ASAs. Sulfasalazine, the oldest oral 5-ASA, is bonded to sulfa, which can cause changes to blood cells over time or allergic reactions, so a patient should beware of those negatives when choosing among available meds. As Judilyn writes, the use of retention enemas in combination with oral med can speed healing in the recto-sigmoid sections of the colon. Many members here can vouch for that. / Old Hat
Old Hat. What's best for pancolitis, Asacol, Lialda or Colazal? I realize these are all the same active ingredient but you seem to feel there may be an advantage and I love to hear it.