I didn't know that - been on the Prednisone since November. Started with 10 mg 2xdaily then weaned down to 2 mg 2xdaily and flared up again in March. Now down to .5mg 1xdaily and this acid reflux has just come on. Good to know it can be a side effect - hoping to get off the Prednisone so then maybe the reflux will stop. In the meantime, taking Prevacid 15mg 1xdaily - started today! Hope it helps the symptoms.