Imuran(Azathioprine) is what made the difference for hubby. Mid May '07 along with 40 mg of prednisone to "jump start" it. We requested a very slow taper on the pred due to being steroid dependant. Started on 75 mg of Aza which was low but within 6/7 weeks there was a noticeable improvement. In Nov Mayo increased it to 150mg more in line with his weight as he was tolerating and metabolizing the Aza just fine. By early Dec he was off the prednisone and it was finally a successful taper for him.
His Mayo Dr requires monthly blood testing to monitor the Aza which is doing just fine for him. This Nov we will have a 3-4 day stay at Mayo for another colonoscopy and other testing as they are just a bit concerned why he still needs the pain meds and want to see if something else is going on in there as they feel he should be in a much better place than he is at the moment. His last visit in May the Dr was hoping he would be in a true remission at that visit.
As far as my husband is concerned he is quite pleased with the improvement and overall ability to have a lot of his life back. What he contends with on a daily basis and the occasional blips he has learned to accept and be grateful that he can function and enjoy his days far better than when he was at rock bottom. His acceptance of his limitations and frequency is just a part of his daily life now and he has learned to deal with it. In comparison to where he was and where a lot of others are at the moment he still feels blessed to have most of his life back.
Hopefully the Imuran will make a big difference for you and your body allows it to work and help you.
61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07 Oct 07 feeling quite normal most days. 150mg Imuran
Zero mg prednisone 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 20 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs Morphine Sulf 15 mg twice daily)Cortifoam enema every other PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month