I have 21 cm. affected, but still procto-sigmoiditis. The difficulty in achieving remission is completely independent of how much of the colon is affected. That is, someone with stubborn, severe proctitis can be more difficult to get into remission than another person who has mile to moderate pancolitis.
Mesalamine in any form (Asacol, Pentasa, Rowasa) made me worse - more D., cramping and bleeding. Colazal helped a little. Steroids added helped a little, but then I was unable to get off them without flaring badly again. Immunosuppressants helped me very minimally. Finally Remicade got me into remission. I know that seems like a really big drug for a pretty limited area of inflammation, but then colectomy would have been a pretty big surgery for that same inflammation, and I was really sick.
I hope you'll find your right combination soon. I just want to say that for me, the benefits of the "big" drugs far outweigh the risks. I've got my life back, and I was on the verge of having to go on disability. Now I eat what I want, go where I want, travel and live a normal life.
Judy - Southern US
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Avascular necrosis in both shoulders is my "forever" gift from Entocort.
Colazal, Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
Co-Moderator UC Forum
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