I use one-half a pill in the mornings, just before leaving the house, when I'm flaring (only then). It helps calm things a little, but doesn't completely stop things so I think would avoid that toxic colon thing. One whole pill makes me uncomfortable, I only do that when I have to run a meeting or it will be difficult or awkward to find a bathroom. I haven't used two pills at once in years. Remember the bottle directions are meant for people with an accutate case of D, not chronic.
A few other remedies for the D have been mentioned here, too, but that's what I do. I've thought about trying the metamucil (pills, because the wafers have gluten).
49 year old female, diagnosed UC/pancolitis 1985, no surgery but much suffering.
Asacol/5ASA maintenance for 20+ years, usually 3 pills 2x day.
Currently tapering off presnisone from lingering flare;
August 2008 sought care of naturopathic doctor. Tested gluten intolerant and started gluten-free, soy-free, etc. diet which resolved flare. Also Replete probiotic, DGL (licorice root, slippery elm), Permeability Factors. Slow-release iron and B-12 shots for severe anemia.