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**NiCoLe**
Regular Member


Date Joined Jan 2008
Total Posts : 39
   Posted 9/15/2008 12:15 PM (GMT -6)   
Just curious what the lowest dose of sulfasalazine that anyone has been on. I am suppose to take 3 pills twice a day, but due to my pregnancy, if I take the pills in the morning, I usually end up throwing them up. I have just been taking 4 pills @ night. Just wondering if this is enough to even do anything. Thanks!
Diagnosed in Jan 2007, but had bowel issues for year
Took Asacol for 1 year (no help) and Prednisone twice (60mg was the most)
Currently taking Sulfasalazine - 4 pills 2x a day
Hospitalized in Jan 2008 and then again in Feb 2008 (IV steroids) for 9 days
Was using VSL #3, but it made me throw up (I'm pregnant and nauseous)
Rowasa enemas as needed
33 weeks pregnant and counting . . . . . .
Prenatal Vitamin
150mg Zantac twice a day (for acid reflux and nausea)


ediekristen
Veteran Member


Date Joined Apr 2007
Total Posts : 1366
   Posted 9/15/2008 1:04 PM (GMT -6)   
Not sure, I was just prescribed this today and it's two pills three times a day for me (so the same dosage). He didn't mention if it was a low or high dose though.

Female, 23, Ulcerative colitis (pancolitis) for 8 years so far; GERD; gastritis; osteopenia in femur head & lumbar spine from long term prednisone use....

Current Meds:
Lexapro 10mg, Lialda 2 pills a day, Rowasa enemas nightly

 
 


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 9/15/2008 2:03 PM (GMT -6)   
I believe that you should take it spread out through the day. I am on 6 per day, I do 2 in the am, afternoon and early evening. I understand if you are throwing up in the morning it would be difficult to keep them down, perhaps if you are usually done throwing up by a certain time, then you can take the first 2 after that.

DOSING: Doses range from 500mg to 2000mg, and dosing intervals range from every 6 hours to every 12 hours, depending on the clinical condition of the patient. Higher doses have also been used. Sulfasalazine should be taken with a full glass of water after meals or with food to minimize stomach upset. Patients with kidney diseases may need to use lower doses of sulfasalazine.

DRUG INTERACTIONS: Sulfasalazine may cause reduced absorption of folic acid and of digoxin.

Have you also been giving a scrip for folic acid?
 
 
Congrats! on your pregnancy, hope your morning sickness ends soon!!


*******Donna*******
 
South of Boston, Ma
 
diagnosed with uc 27 years ago.  Enojoyed 20 year remission with just minor blips here and there (approximately 16 of those years without any meds)
 
In a flare for 2 very long years which Asacol didn't help at all.  Finally in remission again since Jan 2008, can't believe it..............
 
currently on Sulfasalazine 2 tabs 3x day. Folic acid, mesalamine enema once a week. Omega 3, Probiotics, multi vitamin, calcium supplement, Biotin 5000mcg, Fibercon.
 

Post Edited (munchkindd) : 9/15/2008 1:12:50 PM (GMT-6)


IndianaUC
Regular Member


Date Joined Feb 2007
Total Posts : 212
   Posted 9/15/2008 6:01 PM (GMT -6)   
I've never been pregnant so I can't relate, but during my worst flare I had a hard time keeping the morning pills down. If you eat a banana or some toast then take the pills it's easier on the stomach. I would also chew two tums with the pills and that settled things down. Stay away from anything that smells bad to avoid further stomach upset. I know it sounds weird, but anything that smelled...funky....would have me throwing up immediately.
- DXed with "left sided" UC in 1998. DXed with "proctitis" Oct. 2007
- Sulfasalazine 3 500mg tabs twice daily
- 500mg Vitamin C, 1 Multivitamin, L-Glutamine
- Max Acidophillis EC Capsules 350Mg(7 types of bacteria with over 42 billion viable cells) with 50 Mg colostrum & 50 Mg FOS(fructo-oligosaccharides)
- Experimenting with this or that on occasion. Always open to new ideas.
- Colonoscopies - 2 (Due for my next one ASAP)
- Strangely I find that eating a turkey and ham sub from Subway with lots of vegis will help me come out of a flare. Why I don't know. I stay away from fats or my D will just get worse.

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