I believe that you should take it spread out through the day. I am on 6 per day, I do 2 in the am, afternoon and early evening. I understand if you are throwing up in the morning it would be difficult to keep them down, perhaps if you are usually done throwing up by a certain time, then you can take the first 2 after that.
DOSING: Doses range from 500mg to 2000mg, and dosing intervals range from every 6 hours to every 12 hours, depending on the clinical condition of the patient. Higher doses have also been used. Sulfasalazine should be taken with a full glass of water after meals or with food to minimize stomach upset. Patients with kidney diseases may need to use lower doses of sulfasalazine.
DRUG INTERACTIONS: Sulfasalazine may cause reduced absorption of folic acid and of digoxin.
Have you also been giving a scrip for folic acid?
Congrats! on your pregnancy, hope your morning sickness ends soon!!