Changing medicines-help!

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tooth fairy
Regular Member

Date Joined Jan 2008
Total Posts : 98
   Posted 9/22/2008 8:32 PM (GMT -6)   
Hi everyone!

Is it possible to discontinue imuran and start it again at a later date? Will the medicine still be effective when started a second time? I am currently trying to conceive and I'm convinced that the Rowasa enema is the key to keeping my flares in check, not the imuran. My GI was late to prescribe the Rowasa-I didn't start the enemas until 8 months ago, whereas I've been on the Imuran since fall 06. Since imuran is so risky in pregnancy and also not normally recommended for nursing, I'd like to try to come off of it with the hopes of nursing my baby (and lowering my pregnancy risk factors). I don't want to do this though if it means I can't use the medicine in the future. Anyone out there have experience with stopping meds and starting them again?
Erica, 31
Pancolitis, diagnosed July 2006, at age 29
Imuran, Asacol, Rowasa*(new!)
Experimenting with diet, live culture yogurt and probiotics

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 9/22/2008 10:35 PM (GMT -6)   
Hey, Erica, long time no see! Imuran can be stopped and re-started without problems. You don't develop antibodies to it as with Remicade. As to whether or not it will work when re-started, like everything else with this DD, that's a definite maybe. There's no reason it shouldn't work, but then sometimes people take it (or any of the meds we use) for years and it suddenly stops working. But there's nothing specific about this drug that makes it more of a problem to stop and start.
Judy - Southern US 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Avascular necrosis in both shoulders is my "forever" gift from Entocort.
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
Co-Moderator UC Forum
Please remember to consult your health care provider when making health-related decisions.

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