They're either retention enemas, foam enemas, steroid or 5-ASA (like ASacol) as well as supposiories in either steroid or 5-ASA.
Consider UC starts at the rectum....that's why you should/need to be on rectal meds.
It could be that you're not on enough meds treating both ends...not that you're sensitive to 5ASA meds.
*Heather* Status..Asacol 6 (3 twice daily); enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 4(Natural Factors Protec) bedtime + Primadophilus Reuteri Pearls occasionally
~multi-digestive enzymes as needed
~Ranitidine,Pariet (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!