Hi, I have had UC symptoms for over a year and was diagnosed in January 2008. I have not had one remission yet and nothing seems to be working. I tried the foam, Canasa, Asacol and Lialda. (after my insurance finally decided to cover it) I seemed to be progressing with Asacol, but it took forever and it never really went into a remission. The only thing that seemed to stop was the cramping. I have been on Lialda for 2 weeks now and it feels really good to only take pills once a day, but I dont feel myself. The cramping has come back, gets really bad and I have to go to the bathroom a lot more now. Has this happened to anyone else?? Should I go back on Asacol and keep forgetting to take my pills or stay on Lialda, get my correct dosages and suffer a little (for now?) ??