I've been on Lialda for about 2 months now. I'm only taking 2 in the morning, but at one point my doc had me increase to 2 in the morn, 2 in the evening. I started to get a rash on my legs, neck, and stomach, so we cut back to just 2 in the morn, and the rash went away. No other goofy side effects from it since.
Previously, I used Asacol for two years. I was fine at first, but as time wore on, I developped a rash on my legs, and I was horribly exhausted and feeling run-down all the time. It kept my UC in control, but that doesn't do much good if you're asleep all the time. As soon as I stopped the Asacol, I had my first full-blown flare.
I'm hoping that the Lialda won't do the same thing, mainly because I'm taking a lower total dosage of the mesalamine (Asacol, 3 tabs, 3x day = 3600mg, Lialda 2 tabs 1x day = 2400mg). I'm still using a minimal dose of prednisone, plus hydrocortisone enemas every other night, but my flare seems to be going away. I'm going to stop the prednisone this week, and hope that things keep going smoothly.
36 y.o. male
Diagnosed w/ moderate UC back in May '06
Meds & supplements:
Asacol, Florastor, VSL#3, Wellbutrin XL, Prozac, multi-vitamin, Allegra, Lialda, Colocort enema every other night, Prednisone (down to 5mg, YAY!), flaxseed oil, glucosamine.