so you think maybe a short pred course would help? I wonder also about
the pred dose- when really flaring, nothing under 60mgs/day will help- and at that dose, there is no such thing as a short course! With taper time you end up on the pred for 3-4 months! I haven't had the antibody test- there is definitely some amount of antibodies built up in my blood, but both my GI & myself agree that currently, the Remicade is helping enough to justify still being on it. What burns me about
going on pred is this- I went on Remicade initially to try & get off the steroids, as I'd become dependent on them to keep myself in remission. If I go back on them, what does that say? Steroid dependency is definitely a good reason to pursue surgery- I hated my last pred course so much I swore I'd undergo surgery before going back on it. Each course I've been on has been less & less effective. That's why I'm thinking maybe the steroid suppositories, as opposed to a systemic steroid. Ugh...what a crappy choice! I'll be very anxious to hear about
how the steroids help you with the infusion- when is your next one? Mine isn't for another 4 weeks. I can't honestly say that what I eat seems to have much effect- it's more the amount I eat. If I eat a lot, then I have more gas that night, & more bm's the next day, with more urgency. I feel like my GI tract can handle about
1500-2000 calories a day & then it just quits on me. I wonder too if our colons haven't become hypersensitive to food, any food, at this point. After years of inflammation, ya know? As far as Humira goes, I've heard that people who build up Remicade antibodies generally get decent results on Humira. Because of the lack of mouse proteins in Humira, I guess you develop antibodies less frequently with an all-human protein, as opposed to the mouse ones in Remicade. But this is just what I read on here, from posters who have had great luck with Humira. For me, it's definitely worth a shot. I look at it this way- Remicade has bought me a couple pretty good years so far & I'm still planning to stick with it. If I need to go to Humira, hopefully that would buy me a couple more good years. And by that time, who knows what other treatments may be in use for UC? I just don't want to pursue surgery unless my life is totally in the toilet- no pun intended!
diagnosed with UC '02
Asacol- 8 tabs/day
Remicade-10mgs/kg- since 4/07