bowel issues but normal blood markers

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Veteran Member

Date Joined Jul 2007
Total Posts : 714
   Posted 10/24/2008 11:05 AM (GMT -6)   
My bowel goes through periods of perfect BMs to periods of urgency and mucus. Blood is minimal. Yet at all times since I was diagnosed 2 years ago my blood inflammatory markers are normal.
I keep asking my doctor and GI why this is the case but get answers like "that's UC for you". But that doesn't make sense. Either the bowel is inflamed or its not. Why do I get symptoms if apparently I have no serious inflammation in my body.
Does anyone suffer UC type symptoms with normal blood markers?
This is frustrating me!!!
Probiotics and maintenance 5ASA's in rectal form
"Whatever you do in life don't berate yourself too much nor contragulate yourself too much. Your choices are half chance. So are everybody elses'"

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 10/24/2008 11:08 AM (GMT -6)   
None of my three GI's has tracked inflammatory markers because they considered them unreliable in UC. Remember, this DD seldom makes sense.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Avascular necrosis in both shoulders is my "forever" gift from Entocort.
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
"My life is an ongoing medical adventure"
Co-Moderator UC Forum
Please remember to consult your health care provider when making health-related decisions.

Veteran Member

Date Joined Mar 2008
Total Posts : 1580
   Posted 10/24/2008 11:19 AM (GMT -6)   
I do not test positive for C-Reactive Protien levels and I have UC
Moderate Pancolitis
Dx'd 05/2007
8 Pentasa per day (4X2)
Corti Foam p.m.
Probiotics, Bowel Soother, Fish Oil, Calcium, Multi Vitamin and Melatonin
Trying to reduce sugar in my diet but cannot tolerate artificial sweetners
I excersice daily
Did I happen to mention I HATE this disease!!!

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 10/24/2008 11:23 AM (GMT -6)   
Except for my initial diagnosis, all my blood markers have been normal. I wonder though.....could that be because of the medications we are on such as the 5-ASA's which are anti-inflammatories??? Just a thought.
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Year-round allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Spinal Stenosis(?)~Sacroiliitis-epidural injections~bulging and herniated discs C5/C6 & C6/C7~3rd epidural injection 9/4, Neurontin and Skelaxin
To help Healingwell - click here: DONATE


Regular Member

Date Joined Apr 2008
Total Posts : 460
   Posted 10/24/2008 11:42 AM (GMT -6)   
I'm the opposite.  My blood work always comes back horrible when I feel great! 
Female, Age 37
Diagnosed w/c.diff 7/02 when pregnant w/1st and only child during 2nd trimester(wasn't on antibiotics)
C.diff flare within weeks of delivering baby 1/03
Diagnosed with UC 2/03
Current Meds:
75mg 6-MP
Cortenema as needed
Ferrex Forte
Sacchromyces Boulardii 

Regular Member

Date Joined Aug 2007
Total Posts : 255
   Posted 10/24/2008 3:00 PM (GMT -6)   
My blood work has always been negative for markiers indicative of Crohn's and UC, but I didn't get bloodwork done until I was on meds. The blood tests are unreliable, like Judy said.
Tressa 35 (F) in WNY
UC w/skip lesions & stomach ulcers
Asacol 12/day, prilosec twice/day, Canasa as needed

Regular Member

Date Joined Aug 2008
Total Posts : 327
   Posted 10/24/2008 4:25 PM (GMT -6)   
My inflammatory markers were perfectly normal this May when I was flaring (plenty of blood, mucus, and urgency), and in fact that led to a delay in me getting referred to a specialist and being diagnosed. My sed rate is always really, really low. My GI said that for some people it's not a reliable indicator, and I guess I'm one of them.

Prometheus panels also strongly suggested I don't have IBD, either Crohn's or UC, when sigmoidoscopy and biopsies (the gold standard) say UC.

As far as I know, "normal" just means within the usual statistical range of variability. That leaves a lot of wiggle room.
40, female
Dx ulcerative proctitis, 3-5 cm, June 2008 (after 5 weeks of blood and mucous) and still flaring
Canasa 1000 mg suppositories and 2 tsp smooth texture Metamucil nightly
25 mg hydrocortisone suppositories and 1 Garden of Life Primal Defense Ultra in a.m.
Effexor 37.5, Remeron 30 mg, Clonazepam .5 mg (or more) and Trazodone 75 mg for sleep/anxiety
2.5 mg methimazole for thyroid
Trying acupuncture
Osteopenia and other assorted ailments

Veteran Member

Date Joined Jun 2008
Total Posts : 2865
   Posted 10/24/2008 8:21 PM (GMT -6)   

I don't even know what "markers" are?  I know my doctor has not taken any blood so assume he has not looked - just does the scope.  Having my second one on Tuesday. 

I am now taking Reglan and had to start with 1/2 dose because of grogginess - every medication causes me problems so nothing new.  Seems to be ok at 1/2 dose but don't know if it will help or not with symptoms of nausea/sweating, etc.


68 yr. old granny
New diagnosed with proctosigmoiditis - 6/2008
10/3/2008 - agreed to try one Lialda and one Canasa every day due to my sensitivity to all medications and side effects. Colonoscopy 10/28 to reaccess.
Probiotic Align, Prilosec for GERD
Inderol for hypertension,Xanax,Lipitor, multivitamin, calcium w/D, Tylenol

Veteran Member

Date Joined Dec 2006
Total Posts : 517
   Posted 10/25/2008 9:46 AM (GMT -6)   
I've never been able to have blood work determine whether or not I had UC, or if I was flaring. I had the Prometheus test done back in July, and it came back as negative for both UC and Crohn's, basically saying I was healthy. The c-scope a month later showed I was in full blown flare (which I could have told them). As Emory said, a scope is the gold standard. Bloodwork isn't reliable enough.
36 y.o. male
Diagnosed w/ moderate UC in May '06
Meds & supplements:  Asacol, Florastor, VSL#3, Wellbutrin XL, Prozac, multi-vitamin, Allegra, Lialda, Colocort enema every other night, Prednisone (down to 5mg), flaxseed oil, L-glutamine.

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, September 25, 2018 1:57 PM (GMT -6)
There are a total of 3,006,511 posts in 329,346 threads.
View Active Threads

Who's Online
This forum has 161836 registered members. Please welcome our newest member, princesspoopsalot.
330 Guest(s), 15 Registered Member(s) are currently online.  Details
Michelejc, bobmars, oceanfisher58, cashlessclay, Anitas, Admin, Girlie, zack36, JohnBa, Redwing57, dmanIndy, Squarsh, InTheShop, garyi, Envsciguy