Hi Vin- have been on Remicade for about 19 months- first at the 5mgs/kg dose for about 3 months, then at the 10mgs/kg dose since then. I receive infusions every 6 weeeks, & have been at that dosing schedule for about 1 year. I went into a really good, true remission early, but it only lasted thru 2-3 infusions. I developed strep pneumonia, bacteremia, & drug-induced hepatitis after my 2nd infusion, which put me in Intensive Care for 5 days. After that, the following Remicade dose didn't do much at all- not sure if it was due to the interrupted loading dose schedule, or anti-body build-up. So we upped the dose & shortened the dosing time frame & have been doing that ever since. I've been in an ok remission since then- I do get gas, mucous, & have 4-6 formed bm's with major urgency every morning. I have not been on pred since 2/08. I consider myself to be doing ok- I work, go out, eat basically anything I want. I still have some misgivings about being on the drug, especially since I got so sick that one time. But knock on wood, things have been going good since then- no respiratory stuff, no more health issues directly caused by the Remicade. I'd advise anyone to try it. Judy- FYI- Remicade was only FDA approved for rheumatoid arthritis in 2002, so that 10 years of use figure is a little off. It was approved for UC in 2006. That is the only part of the drug that makes me uneasy, the short length of time it's been in use.