They can dry up the body lining fluids, so that could be a bit of a factor. As well, body reactions can involve the whole system ... autoimmune just might want to join the party.
Make sure you get enough fluids, maybe consider to take a fibre supplement to help with the peristalsis...etc..that can sometimes become lazy from taking antihistamines if things are dried out too much.
Keep us posted as to how you're doing, it's good you're getting some relief.
*Heather* Status..Asacol 6 (3 twice daily); enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 4(Natural Factors Protec) bedtime + Primadophilus Reuteri Pearls occasionally
~multi-digestive enzymes as needed
~Ranitidine,Pariet (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!