Sulphasalazine / Sulfasalazine.

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Scottishcammy
Regular Member


Date Joined Nov 2007
Total Posts : 124
   Posted 10/29/2008 12:41 PM (GMT -6)   
Hi, anyone had any experiences of this? I've just started taking it and the hope is it helps my arthritis.
My colitis is under control with the azathioprine I'm taking.
It's really for the arthritis, in the hope of avoiding infliximab or the like, which my rheumatologist was trying to get me to take.
Thankfully my gastroentologist wants to try and treat it with safer drugs (sulphasalazine) first:-)

I'd really like to hear from anyone who has arthritis as well, and found this drug helpful.
Diagnosed Indeterminate Colitis 25/11/2007 (update: told by consultant 15/01/08 in his opinion definitely UC).
150mg Azathioprine/Imuran.


Peety
Veteran Member


Date Joined Mar 2008
Total Posts : 2855
   Posted 10/29/2008 12:45 PM (GMT -6)   
I'm allergic, get a mild rash. I guess that's not uncommon.
I had luck with Voltarin, short term.
49 year old female attorney, diagnosed UC/pancolitis 1985, no surgery but much suffering.
Asacol/5ASA 6x400 mg maintenance for 20+ years; use prednisone & Rowasa for flares. 
August 2008 sought care of naturopathic doctor. Food sensitivity test showed gluten, other intolerances; started diet without gluten, soy, dairy, tomato etc. Replete probiotic first, then Forte pills. 
Achieved remission for the first time in many, many years!? Seemed so, but colonoscopy Oct. 6 proved not so, heavy inflammation in ascending colon & will be using Rowasa again. But I AM better.
 
 


WhiteSox1
Regular Member


Date Joined Oct 2007
Total Posts : 135
   Posted 10/29/2008 1:01 PM (GMT -6)   
That's interesting. I was just recently diagnosed with Osteoarthritis in my spine and I've never heard of the med's you are taking. I'm going to have to talk to my GI doc about that. My other doctor told me to take Aleeve for the pain which really upsets my stomach.
Pancolitis - Diagnosed on 9/6/07
Asacol 4 pills 3x's daily
Imuran 150mg.
Canasa
Multi-Vitamins
Calcium with Vit. D Tablets


Scottishcammy
Regular Member


Date Joined Nov 2007
Total Posts : 124
   Posted 10/29/2008 1:04 PM (GMT -6)   
Azathioprine is the UK name for Imuran mate:-)
When sulfasalazine is metabolised in the liver, it produces mesalazine (asacol). The asacol is basically the modern version of sulfasalazine. The sul' has lots of potential side effects compared to the asacol, but it also helps arthritis (it's also used to specifically treat arthritis).
Diagnosed Indeterminate Colitis 25/11/2007 (update: told by consultant 15/01/08 in his opinion definitely UC).
150mg Azathioprine/Imuran.

Post Edited (Scottishcammy) : 10/29/2008 1:14:35 PM (GMT-6)


WhiteSox1
Regular Member


Date Joined Oct 2007
Total Posts : 135
   Posted 10/29/2008 1:16 PM (GMT -6)   

D'oh!

I have a lot to learn.


Pancolitis - Diagnosed on 9/6/07
Asacol 4 pills 3x's daily
Imuran 150mg.
Canasa
Multi-Vitamins
Calcium with Vit. D Tablets


Scottishcammy
Regular Member


Date Joined Nov 2007
Total Posts : 124
   Posted 10/29/2008 1:23 PM (GMT -6)   
Hey, no worries matey, we all do...that's what this place is for;-)
Diagnosed Indeterminate Colitis 25/11/2007 (update: told by consultant 15/01/08 in his opinion definitely UC).
150mg Azathioprine/Imuran.


Luna0
Regular Member


Date Joined Jul 2008
Total Posts : 83
   Posted 10/29/2008 1:27 PM (GMT -6)   
turn   We all have alot to learn. When do we stop learning?
Tawn 
19 years old, College Student ~WAHOO GO CATS=)
 
Diagnosed in 2004
Currently on:
Remicade
Imuran 3pills/day
Benifiber
And other over the counter meds.


Scottishcammy
Regular Member


Date Joined Nov 2007
Total Posts : 124
   Posted 10/31/2008 2:47 AM (GMT -6)   
Anyone else with sulfa' stories?
Diagnosed Indeterminate Colitis 25/11/2007 (update: told by consultant 15/01/08 in his opinion definitely UC).
150mg Azathioprine/Imuran.


princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 10/31/2008 8:09 AM (GMT -6)   
Sulfasalazine is my maintenance drug - and has been the only drug I've taken for my UC for years now. It's worked great for me. I stay on a maintenance dose - 500mg/4 times a day unless I have a mild flareup, then I increase to 1000mg/4 times a day. I can't speak to it's effectiveness treating arthritis. Have you looked at supplementing with glucosamine?
Diagnosed with ulcerative colitis spring 1999.
 
Maintenance dose sulfasalazine.
Probiotics, l-glutamine and fish oil caps. George's aloe vera juice. Oregano oil antibiotic, antiviral, antifungal. Long-term remission with only minor blips.
 
 


kazygirl
Veteran Member


Date Joined Sep 2007
Total Posts : 955
   Posted 10/31/2008 8:17 PM (GMT -6)   
i had a reaction to the sulpher in sulphasalazine so they put me on mesalazine.
now i have been switched to pentasa (which i think is the same thing)

when i had arthritis, i couldnt really take anything cuz NSAID's are really bad for UC. (non steroid anti inflammatory drugs)
such as alleve, motrin, ibuprofen, naprosen, advil etc...

my arthritis went away on its own after 4 months. was limited to my knees and ankles. UC induced.
sucked!
steph - 32 - female - gold coast australia - UC since 2000
severe UC in descending colon and sigmoid colon ONLY
mesalazine granules 3g x1 a day (much nicer than a million tablets a day)
prednisolone 25mg x1 a day (ick ick and did i say ick?)
enteric coated fish oil -omega 3 (so they get all the way to my colon)
vitamin D3 x1 a day
tumeric capsules - if i remember to take the bloody things.
i still eat what i want, when i want, if i feel like eating at all :(
 
 
 

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