UC, Crohns, Microscopic colits and most other inflammatory diseases are intensified and sometimes seem worse when you are depressed and have anxiety all the time.
Usually I find that I flare when I am stressed or drepressed, maybe this starts the hightened inflammatory response and leads to a flare but I am not sure. I do know that I always feel better when I do not have anxiety and my depression is controlled.
I was DX'd with UC about 3-4 years ago and that really scared the crap out of me. Depression and anxiety went thru the roof and I flared even bigger and harder. My PCP put me on Wellbutrin and Ativan (wellbutrin has a lower chance of D being a side effect) and ativan to calm my nerves. Since I have moved and have a new pcp that is telling me that combo is a bad one. So we tried a few SSRIs (paxil and zoloft) and those only made my D worsen which in turn increases anxiety and drepression. The next one to try is Celexa but I think I might just skip to Effexor (less chance of D) and not try the Celexa.
SSRIs can cause D, especially Paxil, and in some studies it even shows that it causes undetermined colitis in up to 40% of patients. When I found this out Paxil was gone. My mom suffered from a ton of D when she was on Paxil.
All that being said, I will keep trying to find that magic bullet for me that will keep me happy without the added D. My symptoms are almost nonexistant when my mood is good. When my mood is bad then I start to feel physically ill.
March 2005 Dx'd with Ulcerative colitis
Took: asacol, colazal, rowasa, entocort, VSL probiotic
2.14.06 Test results positive for gluten and dairy sensativity! (enterolab)
July 2006 normal c scope and biopsies
Taking: Wellbutrin 150 mg Ativan .5 mg as needed
Gluten Free Dairy free since May 20, 2006 and feeling great