Ok I know that some drugs like 6MP and Imuran can take months and months, and at the other extreme pred can be felt in many ways within minutes or hours, and usually has some clinical response within days at most. So my impatience may come off as ridiculous, but here goes. I am about a week since my first infusion of Remi. So far, I haven't been able to truly notice any difference... starting to worry this will be another dead end while trying to be patient. The only thing that has changed in the past few days is numbers of bowel movements per day. It has gone down from 3-8 down to 1-2 for two days now but they are still muddy or loose, and the gut pain remains unchanged, so it may just be the effect of weeks of higher dose pred. I realize some may (???) take weeks or 2 or 3 infusions to notice it really "kicking in" but I was hoping to fall into that category who seem to experience a big drop in symptoms within a few days of their first infusion. Is there a cutoff where you can know it probably isn't helping and that I should start to fast track surgery?
Pancolitis 20 years ago, full med-free remission 10 years,
Flaring/simmering on and off ever since
10 20 17.5 15 12.5 10 mg 8 7.5 20 mg pred, 100 mg Imuran
Probiotics (Primal Defense and others), TSO,
Turmeric/circumin, boswellia, fish oil, many vits/minerals
Lower-carb version of Specific Carb Diet (SCD), Remicade newbie