sulfalasine side effects

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Regular Member

Date Joined Aug 2008
Total Posts : 55
   Posted 11/16/2008 11:51 PM (GMT -6)   
hi people..i need some advice.
my doc switched me from asacol to sulfalasine bcz all my joints r aching n am really afraid of bcz i heard the side effects r pancreas probs,liver probs, fall in WBC n anemia sad
am so so stressed confused
am taking it since 2 weeks n no improvement
wat wil happen if my WBC fall completely? sad

Regular Member

Date Joined Jan 2005
Total Posts : 352
   Posted 11/17/2008 12:22 AM (GMT -6)   
hi s-girl,
It sucks but hang in there.  Could be coincidental that the joints are acting up.  I wouldn't be so quick to blame the meds on it.  Don't you find it odd and amazing that the colon has effects on the darn joints.  It blows my mind.  I encourage you to try to remain optimistic.  Enjoy each day as much as you can.  Try to dwell on what's good.  It'll be a challenge, but with some work you can find something positive to focus your energy on.  Smile.
Mild to Moderate Left Side UC since 10/2002, Joint Pain since 10/2004
Strict SCD 7/2004-12/2005
Prednisone 8/2004-10/2004
Remission since 9/2004
Daily Meds:
 1500 mg Pentasa, 150 mg Zoloft, 30 mg Baclofen, 10 mg Ambien

Regular Member

Date Joined Aug 2008
Total Posts : 55
   Posted 11/17/2008 2:22 AM (GMT -6)   
ya it off work since 3 months bcz of knees n left hand r so swollen that i cant do typing with only 1 hand bcz the other is swollen..

i really wana know how much time sulphalasine takes to work

New Member

Date Joined Oct 2008
Total Posts : 17
   Posted 11/17/2008 3:47 AM (GMT -6)   
hi ive found that i have a sensitivity to the 5asa group which sulphalasine is in some of them ,symptoms ranged from increaed bm ,urgency, incontinence and generally a worsening of my uc instead of improvement. last one i took was pentasa granules 2g i had 1 satchet and ended up in hosp later that night with violent diarrohea and vomitting , put on drip to rehydrate me .not impressed especially since i had mentioned to my dr about being sensitive to 5 asa group, he felt i hadnt had a high enough dose to combat uc how wrong was he .He now has written in my file allergic to metasalazine.So good luck but if symptoms worsen not improve tell him straight away....


no remissiom to speak of just commenced imuran .fingers crossed!!!!!!!!!!!

Regular Member

Date Joined Aug 2008
Total Posts : 55
   Posted 11/17/2008 5:05 AM (GMT -6)   
as for me..i dunno if am allergic or not tp 5asa..was on asacol for3months but never felt good

thks beefree..u young 23..uc sucks

Regular Member

Date Joined May 2008
Total Posts : 65
   Posted 11/22/2008 11:13 PM (GMT -6)   
I have been on sulfasalazine since May of this year. First, I have absolutely zero side effects for the pills themselves. I am seriously in love with them. They are miracle workers! They also began working for me in only a few days and by two weeks I was in full remission. Also, I used to be anemic and now my iron levels are normal and I only take a regular multi-v a day. I used to take separate iron pills.

I do still have joint paint and fatigue. My doctor tried to up my dosage of the sulfasalazine for a while and though it fixed the joint pain, my body couldn't handle the high dosage, I started getting massive headaches and stomach aches and my UC symptoms came back, so I had to go back down to the dose that controls my UC but does nothing for the joint pain and tiredness I feel.

Hope that helps your questions.
27 years old, Female, NYC
Diagnosed with severe UC on May 13, 2008 (though I'd apparently had it for years)
500 MG Sulfasalazine two pills x3 a day
Daily Multi-V, Folic Acid

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