A mouse model that accurately created and treated IBD (and my own experiment)

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relativelyquantum
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Date Joined Sep 2007
Total Posts : 196
   Posted 11/27/2008 9:20 PM (GMT -6)   
I'm not sure if this has been posted in the past. 
 
 
On side note: I don't think they are suggesting antibiotics is the end-all be-all.  I recently had a fever and my doc put my on Cipro and Flagyl two nights ago, the same as in the study, interesting enough.  My UC symptoms have returned pretty bad yesterday, but subsided some today.  One of the things that helped me last year and I hope to confirm this year is by following antibiotics with a heavy dose of probiotics about 2 hours after each dose.  I'm also adhering to the Candida Diet to hopefully starve out/ kill any other microbes.  I'm really curious as to why I haven't seen any studies on this.  The closest was the fecal bacteriotherapy.  Anyone know of any others?

Post Edited (relativelyquantum) : 11/27/2008 8:26:02 PM (GMT-7)


DocGonzo
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Date Joined Dec 2006
Total Posts : 151
   Posted 11/28/2008 4:11 AM (GMT -6)   
Anti-MAP maybe? And from the same guys that brought us fecal bacteriotherapy, i.e. Dr. Thomas Borody et al.! Basically, what they claim is that Crohns disease is caused by an especially difficult to treat kind of bacteria called Mycobacterium Avium Paratuberculosis (thus - MAP) and that by using a combination of mycobacterium killing antibiotics one can force the bacterium into statis, and bring about a very long term remission, if not a cure. The antibiotics they use are commonly used for tuberculosis and leprosy (since those diseases are also caused by mycobacteriae), and they have had some remarkable results in the past few years, unfortunately, they are still unable to actually kill off the bacteria since the antibiotics can only destroy the active form of the microorganism, and not the spores it creates. These spores can hybernate for years, and reactivate themselves when the conditions are right, so the antibiotic therapy needs to be VERY long term, we're talking 3-4 years here at least. Anyway - Google "anti-MAP therapy", "Mycobacterium Avium Paratuberculosis" and "Myoconda". You can also check out www.cdd.com.au, that's Dr. Borody's clinic, and they have a section where you can download published articles, many of them deal with anti-MAP therapy.
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