Gargamel....if you have exhausted all the testing to prove that you don't have anything else going on in your colon (invaders), meds aren't working and your quality of life is declining, I'd suggest surgery.
I personally don't think it's good for one to live with a diseased organ that's distressing the body having it in constant defensive mode.
I, if I were in your position, would have it as the next option.
*Heather* Status..Asacol 6 (3 twice daily); enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol (dicyclomine) 20mg as needed
~Probiotics....(Natural Factors Protec 2 or 3 + 1 or 2 Primadophilus Reuteri Pearls @ bedtime
~multi-digestive enzymes as needed
~Ranitidine,Pariet (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!