I don't know the answer to that question. My hubby was just increased to 200mg from 150. Since we incorporated the Mayo Clinic in his care which is a year now, his Dr at Mayo prescibes his Imuran (azathioprine) on a month to month basis only because he insists on monthly labs for AST, CBS, ALT (If I have my initials correct). Once he gets the lab results and reviews them his nurse phones in a month's supply of medication. We do this every month - sometimes it is a pain if the lab hasn't faxed the results I need to call them and have them re-fax it. I have a chart and make sure I allow a full week for the entire process so we won't run out of medication.
His lab work has been fine and since the UC is slow to respond to a remission is the reason he increased it to 200. My husband's weight is approx 180 lbs.
I was initially concerned about
this drug which started out at 75mg (his local Dr was ultra conservative starting him on the medication to begin with) and when increased to 150mg his Dr @ Mayo assured me not to be overly concerned as he insists on the monthly monitoring to keep close tabs on it. He told me this is a "safe" medication when monitored properly. Sooooooooooooo you might want to have a little more dialogue with your Dr especially with the higher dose you are on if you have any questions and are concerned. You need to feel comfortable and assured regarding your care.
I hope and pray the trust and confidence we have with the way his care is being managed is correct. I have no problem with asking questions on his behalf so we can stay as informed as possible.
61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07 Oct 07 feeling quite normal most days. 150mg Imuran
Zero mg prednisone 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 20 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs Morphine Sulf 15 mg twice daily)Cortifoam enema every other PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month