Both Lialda and Asacol cause fatigue in me, as well as a mild rash on my legs and headaches, but both drugs also keep my UC under control to point, which is why I'm still taking them. I keep thinking that there is a drug that won't have annoying side-effects in me, so I'm going to be trying something new soon, but I'm not sure what at this point. For those who tolerate 5-ASAs, they are good maintenance drugs. Adding a probiotic is also really helpful.
36 y.o. male
Diagnosed w/ UC in May '06, had symptoms since '99
Meds & supplements: VSL#3, Lialda, Allegra, multi-vitamin, Wellbutrin XL, Prednisone, fluoxetine, flaxseed oil, magnesium, and vit B-12.