Mesalamine question

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Matt 1977
New Member

Date Joined Dec 2008
Total Posts : 1
   Posted 12/15/2008 1:51 PM (GMT -6)   
I'm on my second brand of mesalamine (Pentasa) and within hours of taking it I get severly nauseated and loss appetite. This happened on the last mesalamine drug I took. Is it possible to be allergic to all of these drugs? Any response would be appreciated.

Elite Member

Date Joined May 2003
Total Posts : 30999
   Posted 12/15/2008 2:34 PM (GMT -6) doesn't sound like an allergy, what is the amount you took and did you take it with food?

UC flares can cause nausea....I have nausea often. I do take an antispasmodic called dicyclomine.

Some foods can cause nausea..

What other meds are you on at this time?

Where in the colon is your UC, limited or throughout?

low in the rectum inflammation can cause nausea...if it's limited there.

Welcome to the forum!
*Heather* Status..Asacol 6 (3 twice daily); enemas every 5th night
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol (dicyclomine) 20mg as needed
~Probiotics....(Natural Factors Protec, Primadophilus Reuteri Pearls, Natural Factors Ultimate)....1 each  @ bedtime
~various digestive enzymes as needed
~Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

Regular Member

Date Joined Oct 2008
Total Posts : 67
   Posted 12/15/2008 2:36 PM (GMT -6)   
It's not an unusual side effect - somewhere between 1 to 10 percent, apparently. I'd suggest talking to your doc if the nausea is severe, as he/she may want to try some alternatives.
UC - diagnosed Sep 2008 - awaiting colonoscopy to determine extent
Omeprazole 2 x 20mg
Prednisolone 15mg
Calcium (Adcal-D3) 1500mg
Mesalazine 8 x 500mg
Mesalazine foam enema
Multivitamins x 2
Omega 3

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