The 6MP takes from three to six months to kick in. I had to take it along with the prednisone. I noticed a difference about three months into my regimen. Symptoms subsided...bleeding gone was the first thing I noticed, then urgency subsided. Now I have normal bowel movements about once or twice a day. Good luck!
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!! Hope I don't jinx myself. Off the prednisone since 11/01/08...now see if I can stay off for longer than two weeks. Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.