I would think Imuran would lower the white count. I am on 6MP and my white count was down to 2.4. I am NOT happy about this but my GI doctor said that the low white count signifies that the 6MP is doing its job. Yeah, but I have to be extra careful about germs. With a white count that low I can catch anything that comes down the pike and don't have the antibodies to fight it off!
Another thing. I was on prednisone for seven months last year. My white count never went above 7,000.
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!! Hope I don't jinx myself. Off the prednisone since 11/01/08...now see if I can stay off for longer than two weeks. Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.