I believe I am an example you are looking for. May, 2008, a colonoscopy showed me to have proctosigmoiditis - rectum and up left side - forgot how far. I took several medications and rectal meds and because I became sensitive to them had to stop all mesalamines which were helping. Then my gastro doc wanted another scope to see how it was and how to treat it further - if I needed strong drugs or steroids, etc. He did another scope in November and found it now confined to rectal area. He said it starts in rectal area, moves up and usually heals from top to bottom. Rectal area, however, is so often the hardest to get healed and into remisiion. My next move is hyrocodone enemas starting next week for two weeks at least.
I am 68 and have IBS and a sigmoidocopy (first 5 feet of colon) about 8 years ago showed no sign of UC.
68 yr. old granny
New diagnosed with proctosigmoiditis - 6/2008
Colonoscopy 10/28 showed only 2 cm. left to heal in rectum - going to try Proctofoam first.
Probiotic Align, Prilosec for GERD
Inderol for hypertension,Xanax,Lipitor, multivitamin, calcium w/D, Tylenol
January 9 - doctor changed me from Protofoam to hydrocortisone enemas for two weeks - wish me luck.