Remicaide dosage change

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Regular Member

Date Joined Apr 2006
Total Posts : 35
   Posted 1/18/2009 8:40 PM (GMT -6)   
Has anyone ever had more dosage of remicaid. I am not responding well to it anymore after 2 years. I go every 8 weeks and receive the standard amount. But now, my Dr. wants to keep me going every 8 weeks but receive a higher dosage of this. Any luck out there? Advice?
24M-buffalo ny
Ulcerative Colitis --- been sick for 10 months---
15 pills of asacol
75mg of 6MP ( waiting for it to kick in )
probiotics ( not sure if they are working )
Cort enemas
Mesalimine enemas ( both of which are hard to hold )
Remicaid here i come soon

New Member

Date Joined Aug 2008
Total Posts : 4
   Posted 1/21/2009 2:42 PM (GMT -6)   

after being on Remicade for several years at 5mg/kg, back in August of 2008 my doctor increased the dosage to 7.5mg/kg as I wasn't responding to it as good as I used to.  And now after several infusions of 7.5mg we're going up to 10mg/kg for my next infusion as I'm still not responding to it well enough.  I'm just afraid that 10mg/kg will not have any effect.  Remicade has been my wonder drug for soooo long.  I'm also on 8 week infusions.


My doc tells me that 10mg/kg is the standard dose for RA patients but that I have been on a lower dosage from the beginning.  I have also heard from nurses at the infusion center where I go that they know a lot of patients who develop immunity to Remicade.


I hope this helps.

Dx: UC - Since Feb, 2003
Rx: Remicade, VSL#3DS

Regular Member

Date Joined Dec 2007
Total Posts : 354
   Posted 1/21/2009 4:21 PM (GMT -6)   
I am on 10 every 4 weeks
Jessica 27/F
Entorcort 9ml
Lialda 2.4GM
Citalopram 20 MG
omeprazole(for acid reflex)
Tried (Entorcort EC 9ml/day and Prednisone, Asacol ,colazal, Culturelle, dicyclomine)

Veteran Member

Date Joined Mar 2008
Total Posts : 1202
   Posted 1/21/2009 10:04 PM (GMT -6)   
We went for 5mg per kilo to 10 mgs per, in about 8 weeks. The first dose (ever )helped, and the 2nd and 3rd did not change much--edge of a flare. The last does of 10 mgs, kicked in a stabilization that has lasted 3 whole weeks..
Don't give up. We are ok for now and holding our own for the first time in a year.
Daughter,15 diagnosed 1-08 w/ UC .
Asacol, Prevacid, Flagyl, Prednisone 50mg, major flare, now off!, Hosp. four x this yr. Low residue diet still, an
6MP, Colazal ,horrible acne/moon for awhile- No more Pred,but 6mp isn't working. Cortifoam enemas 4xweek
Trying probiotics, Niferex, fish oil, and Mangosteen for kicks.
Had 4th infusion of Remicade(12-08), and still on all of the other drugs, except Flagyl and Pred. Better, no remission. In a drug trial for children. Living on a flare's edge.

New Member

Date Joined Jan 2009
Total Posts : 2
   Posted 1/23/2009 1:03 AM (GMT -6)   
Hi I had been on the same dosage of REMICADE as  you....then it started to loose its efectiveness. As a last stab attempt my Dr. has put me on double the amount (10 something) and I go for infusions every 4 weeks..........and I'm finally starting to feel better.My DR said if this dodnt work, they were going to switch me to HUMIRA but I would have to give myself the shots....EWWW  so I hope I can stay with the Remicade.
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