I am on 6-MP since almost 2 months and I felt a relief after only two weeks. I said it before that it might be conincidence, but I have a track record of drugs working very quickly for me than for the average person. In the beginning I had to deal a lot with dull headaches (tolerable, but annoying), slight nausea (eating Altoids helped me in that department) and an extreme tiredness one hour after taking 6-MP. I take it at 6 PM and now, it helps me sleep and I totally like that (I am insomniac since years, on and off). I still get some slight headaches and dizziness and I need like 10 hours of sleep, but it is okay for me and better than not sleeping and suffering all the time. Haven't experienced any hair loss (yet). Oh, and in the beginning I had a rash, but I am not sure whether that is from 6-MP or getting of Prednisone. And the side-effect described as "discoloration of skin" has given me more freckles. I am a redhead with very light skin and I already had some freckles (I am of Irish and Scottish heritage, so there you have it! ) but I get more and more - not really a problem for me. It's kinda cute if I might say so!
We are all worried about the side-effects and long term effects of drugs, but I have reached the point in my 12 year "career" with UC where I care less and less about tomorrow, but only about today. It is impossible to plan a future with UC (please read, I said TO PLAN, not TO HAVE) since the disease is so moody and unpredictable that I want to feel good NOW. And we all can get cancer and stuff that is described with 6-MP as a possible long term effect without taking 6-MP or even taking anything. That is at least how I see it.
WishfulMA, I see that you are on 50 mg of 6-MP. Are you particularly light in your body weight or young to be on such a low dose? It was my impression that 75 mg is always the starting dose and it will be lowered or increased after the initial few months? Just curious.
Scarlett, 38 yo., TX
Pancolitis since 3/1997
Worst flare of my life from 8/2008 until mid 12/2008 - bye bye flare! Was about friggin' time ...
6 x Asacol a day
0 mg Prednisone (stopped Dec 14, 2008)
75mg 6-MP (started Dec 1, 2008)
Flintstones Complete Vitamins