Probiotic enemas? Why not any stuedies on them?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

jpm
New Member


Date Joined Dec 2008
Total Posts : 14
   Posted 1/28/2009 12:39 AM (GMT -6)   
Do you know any research studies or reports on probiotic enemas? This time I don't mean fecal transfusion but inserting specifics probiotic enemas instead of just taking them in oral form. I have not found any. This seems very strange for me because it has been found that probiotics are very useful and they are recommended and studied for many diseases. However if you have some inbalance in rectum, for instance, it would seem much more effective to insert these directly there instead of eating them which results in very low count in the end area (colon and rectum). However,  these doctors and researchers have made extensive studies and clinical use on 5-ASA type of substance, corticosterodes and many other substances as enema form. Why are they avoiding less harmful but probably more effective probiotic enemas.

princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 1/28/2009 10:35 AM (GMT -6)   
Because probiotics can't be patented and pharmaceutical companies can't benefit financially from them. There are few studies of natural, alternative treatments because there are no huge companies willing to fund their research. Also, if there was a highly effective, natural treatment, millions of IBD patients wouldn't need their maintenance medications - resulting in a huge financial loss for both pharmceuticals and physicians.

The Centre for Digestive Diseases in Sydney, Australia is one clinic that has been studying and using probiotics - both orally and rectally - and has had much success. From their Web site:


Researchers at the Centre for Digestive Diseases have been trialing the use of living organisms to treat ulcerative colitis on the basis of restoring the balance of healthy bacteria in the bowel. Our results are at the forefront of world research in this field and may eventually provide a valuable alternative to the current immunosuppressant medications with the added benefit of no side effects.


Diagnosed with ulcerative colitis spring 1999.
 
Maintenance dose sulfasalazine. Probiotics, l-glutamine, vitamin D and fish oil caps. George's aloe vera juice. Oregano oil antibiotic, antiviral, antifungal. Mostly grain-free and dairy-free diet. Long-term remission with only minor blips.
 
 


MAD
Regular Member


Date Joined Jan 2009
Total Posts : 20
   Posted 1/28/2009 1:01 PM (GMT -6)   
princesa said...
Because probiotics can't be patented and pharmaceutical companies can't benefit financially from them. There are few studies of natural, alternative treatments because there are no huge companies willing to fund their research. Also, if there was a highly effective, natural treatment, millions of IBD patients wouldn't need their maintenance medications - resulting in a huge financial loss for both pharmceuticals and physicians.

The Centre for Digestive Diseases in Sydney, Australia is one clinic that has been studying and using probiotics - both orally and rectally - and has had much success. From their Web site:


Researchers at the Centre for Digestive Diseases have been trialing the use of living organisms to treat ulcerative colitis on the basis of restoring the balance of healthy bacteria in the bowel. Our results are at the forefront of world research in this field and may eventually provide a valuable alternative to the current immunosuppressant medications with the added benefit of no side effects.


This is true. I'm very thankful for the research, development and guidance Australia’s Centre for Digestive Diseases has undertaken. So far so good for me. I'm off all meds and currently have no reason to see my GI. I believe if a fecal transplant does not work 100% for you it will most certainly improve your condition by at least 50% - 60%. That goes a long ways for most people. It could mean the difference of losing your colon or keeping your colon. It could mean getting off of steroids verses increasing the dosage. It could mean having less frequent flares of less intensity. The best thing about it is you could always do another “top up” infusion or use another donor until you are 100%

princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 1/28/2009 1:09 PM (GMT -6)   
Well, fecal infusions and probiotic infusions or enemas are two different things. The OP is asking specifically about probiotics.
Diagnosed with ulcerative colitis spring 1999.
 
Maintenance dose sulfasalazine. Probiotics, l-glutamine, vitamin D and fish oil caps. George's aloe vera juice. Oregano oil antibiotic, antiviral, antifungal. Mostly grain-free and dairy-free diet. Long-term remission with only minor blips.
 
 


MAD
Regular Member


Date Joined Jan 2009
Total Posts : 20
   Posted 1/28/2009 1:21 PM (GMT -6)   
princesa said...
Well, fecal infusions and probiotic infusions or enemas are two different things. The OP is asking specifically about probiotics.


Actually there not that far off from each other. Fecal transplant otherwise known as Human Probiotic Infusion is the ultimate probiotic. The difference is the probiotics in human feces have the ability to implant themselves. You mentioned Australia’s Centre for Digestive Disease's has been studying probiotics. Well their studies entail Human Probiotic Infusions not manufactured over the counter probiotics.

jpm
New Member


Date Joined Dec 2008
Total Posts : 14
   Posted 1/29/2009 12:48 AM (GMT -6)   
Yes, I think fecal transplant is a very good thing and is not fundamentally different from more regular probiotics. However, I do think that regular probiotics would be easier to standardise (no donor specific) and even more easier to use. Maybe not that effective but I simply don't understand the reason they (doctors) don't even try probiotic enemas but continue recommending these other things even if they prove ineffective.

Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2832
   Posted 1/29/2009 8:51 AM (GMT -6)   
A quick pubmed search did yield some hits on probiotic enemas but still with rats, not humans. E.g. (paste it as one string if it doesn't click as a link)
 
 
which indicated some benefit.
 
I agree with Princesa on the funding issue- it's not that pharmaceuticals are conspiring to suppress anything, but there is simply no incentive i.e. money in funding non-drug approaches (although individual probiotic strains can be patented if newly discovered).  The same dilemma is faced with helminths (parasitic worms) as therapy- existing worms can't be patented (although Weinstock HAS patented TSO as a therapy, so go figure!- but I don't see how you can succeed in court for an organism that already exists and is long-discovered, in nature.)


Pancolitis ~20 years, once had a full med-free 10 year remission,
but flaring/simmering on and off for years, allergic to all 5ASAs
12.5ish mg pred, 100 mg Imuran TCM (acupuncture & herbs)
Probiotics (PD, Cust.Probiot., Culturelle, VSL3, etc), DMSO, TSO, hookworm
Turmeric/circuminboswellia, fish oil, many vits/minerals
Lower-carb version of Specific Carb Diet (SCD), Remicade
 
 
 

Post Edited (Probiotic) : 1/29/2009 7:58:53 AM (GMT-7)


jpm
New Member


Date Joined Dec 2008
Total Posts : 14
   Posted 1/29/2009 12:52 PM (GMT -6)   
Thanks. They didn't say the specific type of probiotic in the abstract.
New Topic Post Reply Printable Version
Forum Information
Currently it is Monday, June 25, 2018 11:10 AM (GMT -6)
There are a total of 2,975,044 posts in 326,238 threads.
View Active Threads


Who's Online
This forum has 161322 registered members. Please welcome our newest member, exlibris.
427 Guest(s), 11 Registered Member(s) are currently online.  Details
borrelioburgdorferii, BnotAfraid, Farz53, Jasperilla, tarhoosier, teddy9, Girlie, sierraDon, Ticsic, RobLee, joee