This is what my NP and I determined from using the enemas and foam.
I had a full scope October and it showed some improvement from May scope. In that time I had tried about every oral medication in the mesalamine group AND Canasa. (cannot tolerate any of them long enough to help) After that scope (which doc said showed confined to rectal area) I was on Proctofoam for a few weeks - stayed about same - daily bleeding and mucous but only 2 or 3 bms - never more.
BUT, because I was not getting into remission doctor prescribed hyrocortisone enemas for two weeks. I gradually got worse - more blood, more urgency more cramping. So, yesterday I had a sig scope and yes the UC has moved about 4 inches up the colon - left side. Either the enemas made it worse or they were just not doing anything and it spread - no way to tell for sure.
I will start prednisone on Saturday and a taper for three months starting with 40 mg. for two weeks. Then maybe 6MP. Wish me luck and I sure hope you will also get help!
68 yr. old granny
New diagnosed with proctosigmoiditis - 6/2008
Colonoscopy 10/28 showed only few cm. left to heal in rectum - tried Proctofoam for weeks - no luck.
Probiotic Align, Prilosec for GERD
Inderol for hypertension,Xanax,Lipitor, multivitamin, calcium w/D, Tylenol
Tried hydrocortisone for two weeks with no change.
2/3/2009 - sigmoidoscopy showed about 30 cm. involved but mild - starting on prednisone only 40 mg. taper on 2/7/2009.