Canasa Suppositories

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Regular Member

Date Joined Jan 2004
Total Posts : 40
   Posted 2/8/2009 7:36 PM (GMT -6)   
Does anyone have much experience with Canasa suppositories?  I am currently in a flare and my GI gave me a 9 day sample and also a prescription for more.  I haven't really noticed them helping at all, but on this 10th day I sent my hubby to pick up the actual prescription and I was shocked that they were $75 for one month supply, too much money for us right now.  My question is do they take a while to work or should I know by now if they're helping or not since I've been using them for 9 days?  I have seen no improvement since starting them and continue to have blood & loose stool several times per day.  I am thinking about returning the prescription for refund, but was wondering if anyone has had the experience that they don't really kick in for several days, few weeks, etc.

UC 2002
Colazal 9 per day, 125 mg azathioprine
calcium, multivitamin, probiotics, cold liver oil, Biosil, B12

Regular Member

Date Joined Jan 2006
Total Posts : 358
   Posted 2/8/2009 8:11 PM (GMT -6)   
I've used and am using them now. At the height of my flare I couldn't use them because it hurt so much!

But yes, Canasa is expensive-- and from what I hear, no generics so they make it very expensive. With that said, they are helping me continue the battle, along with suspension enemas and Humira.


Began Humira on 10 Jan 2009

Second injection: two pens on 24 Jan 2009

Third injection: two pens on 07 Feb 2009

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 2/8/2009 8:33 PM (GMT -6)   
It depends on where your inflammation is. The suppositories only treat the rectum but if you have inflammation higher up, they will do no good. However, you can "stack" them, meaning insert one and then another. You can use up to 3 Canasa's a day with no ill effect. But I think it would be easier if you were to try the enemas instead if indeed the inflammation is higher up. Rowasa has a generic form called Mesalamine enemas but they are rather pricey too - not quite sure how much they are though. Do you know the extent of your Uc?
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Year-round allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis-epidural injections~bulging and herniated discs C5/C6 & C6/C7~3 epidural injections-worked great!, OA in my fingers -Celebrex and Tylonel Arthritis
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Forum Moderator

Date Joined Dec 2008
Total Posts : 16744
   Posted 2/8/2009 9:19 PM (GMT -6)   
I use Canasa. I remember when I first picked up the prescription, I had to pay about 150 dollars for 60 suppositories - 75 sounds pretty average. I had insurance and it was still $150 for some reason.
I now order from Canada and it's about 120 for 60 suppositories with no insurance. They call it Salofalk in Canada.
Do you use it morning and night? I was using it just before bed for a while and it wasn't helping so much, now I am using it 2x a day and I am feeling a lot better, no more blood or mucus but still some D... I also take Asacol.
When I first took Canasa, I think my UC was very mild and responded well in just a few days. Now it takes a lot longer to get things under control.
I would give it a little more time or try 2x a day if you're only using it once.
I spoke to Axcan Pharma and they have an assistance program. You should check out their site. If you qualify you can get free drugs.

Diagnosed with proctitis in March 2007 - Treated with Canasa 2x Daily
Diagnosed with UC December but had symptoms months ago - Treating with Asacol (feel hopeless)

Regular Member

Date Joined Feb 2009
Total Posts : 473
   Posted 2/8/2009 10:57 PM (GMT -6)   
i take canasa when i'm in a flare. I have proctitus, in the rectum and they do really good things for me. 2x/day when not doing so well. never hurt or anything, i've carried them around and put in whle out and about, no biggie really

Regular Member

Date Joined Apr 2008
Total Posts : 44
   Posted 2/9/2009 8:17 AM (GMT -6)   
I have been in remission but I continue to use one Canasa a day because it has been the most effective drug in my treatment. One thing that I have noticed when flaring is that when the Canasa is "attacking" something when I expel the leftovers the next morning it has a kind of purplish color to it. When I expel it in remission it's the same color as it was originally. You might be able to tell whether the Canasa is having an effect by whether it is changing color. If it's not and you're not getting better it might not be worth the expense.
dx UC Dec. 2001
currently in remission
Meds: asacol 6(400mg)/day
         entocort 3(3mg)/day
         canasa 1(1000mg)/day
         Culturelle 1/day

Veteran Member

Date Joined Aug 2008
Total Posts : 5975
   Posted 2/9/2009 9:00 AM (GMT -6)   
     I have ulcerative proctitis and while hospitalized last year I could not retain the enemas they were giving me so the GI doctor put me on Canasa.  They seemed to help but not as great as the enemas.  When my condition improved I went back to using the enemas one night and Canasa the next until I used up all the Canasas.  Yes, they are very expensive and I have insurance!
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!!  Hope I don't jinx myself.  Off the prednisone since 11/01/ see if I can stay off for longer than two weeks.  Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.

Regular Member

Date Joined Feb 2007
Total Posts : 212
   Posted 2/9/2009 9:32 AM (GMT -6)   
Canasa works in one night for me. It only works in the rectum however. So if your inflammation is higher up then they won't work for you. Without insurance Canasa for me is over $350 for a 30 day supply.
- DXed with "left sided" UC in 1998. DXed with "proctitis" Oct. 2007
- Sulfasalazine 3 500mg tabs twice daily
- 500mg Vitamin C, 1 Multivitamin, L-Glutamine
- Max Acidophillis EC Capsules 350Mg(7 types of bacteria with over 42 billion viable cells) with 50 Mg colostrum & 50 Mg FOS(fructo-oligosaccharides)
- Experimenting with this or that on occasion. Always open to new ideas.
- Colonoscopies - 2 (Due for my next one ASAP)
- Canasa 1000mg @night. Started Oct. 23, 2008
- Niferex-150 Forte 1 capsule 2x Daily

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