After a good trial with rectal meds, etc. don't be afraid to try prednisone - after all is exhausted certainly - in my opinion! I tried all mesalamine suppositories, enemas, pills, and then hydrocortisone enemas and Colazal, etc. Everything made my flare worse and I have not been in remission since diagnosed.
I am on 6th day of prednisone. Don't know the end result of course - but happy right now. I feel about 80% better - regular bm (two or three at most in mornings) and today FINALLY - no blood!! Cramping is only little with some gas but I have IBS also so could be that hotdog! My doctor is talking 6 MP as a maintenance when I taper from prednisone. It is scarey but I will tell you right now I feel so great I don't mind trying what I have to. Many get into remission with 5ASA's and enemas, etc. but I didn't - hope you can. Being your are 30 years younger than I am is definitely a consideration - future affects of these "tough" drugs!
68 yr. old granny
New diagnosed with proctosigmoiditis - 6/2008
Colonoscopy 10/28 showed only few cm. left to heal in rectum - tried Proctofoam for weeks - no luck.
Probiotic Align, Prilosec for GERD
Inderol for hypertension,Xanax,Lipitor, multivitamin, calcium w/D, Tylenol
Tried hydrocortisone for two weeks with no change.
2/3/2009 - sigmoidoscopy showed about 30 cm. involved but mild - starting on prednisone only 40 mg. taper on 2/7/2009.