Trouble getting pregnant on asacol/lialda?

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New Member

Date Joined Jan 2009
Total Posts : 13
   Posted 2/12/2009 11:23 AM (GMT -6)   
My husband and I have been trying for about 6 months now and haven't had success... Just started my period again today which of course has thrown me into a crying spell and hating this disease even more because it's holding me back from what my normal life should be. Has anyone noticed that the Asacol or Lialda has caused complications in conceiving? I'm seeing my GI on Friday and am going to ask him.. I think I'll also make an apt with my Gyn... confused cry
23 year old female
Diagnosed with UC in Oct 2007
Hospitalized 2x in 1 year
3 pills daily of Lialda
2 Canasa daily
Fish oil
Prenatal Vitamins
Newly on the spinach sunflower regime
No white flour, no refined sugar, no potatoes, no white rice

Previously on: Prednisone 100 mg, Colocort, Asacol, Rowasa

Mamas Boys
Veteran Member

Date Joined Oct 2005
Total Posts : 1460
   Posted 2/12/2009 6:57 PM (GMT -6)   
It took me 10 months to get pregnant with my first.  This was pre diagnosis and I totally thought there was something wrong with me.  I also used to get thrown and have a sobbing spell every time I got my period.  My hubby didn't know what to do with me.  When I finally got pregnant I was so relieved.  And when I spoke to my OB/GYN - he actually brought it up first.  He said that many people get crazy when they don't get pregnant within their first 2-3 cycles - but that it is perfectly normal for it to take up to a year to conceive.  I would say don't sweat it.  The more you stress about it - the less likely that it will happen.   Just relax and take it slow - it will come.  And have fun trying!!!  :)   (Just for the record - I got pregnant with my second one my first cycle off the pill.  Go figure!)

Regular Member

Date Joined Jun 2007
Total Posts : 48
   Posted 2/12/2009 7:42 PM (GMT -6)   

I have been trying to get pregnant for a year and a half.  My ob/gyn seems to think that my UC and PCOS are related and that the UC only compounds my problems.  I'm not on either of the medicines you mentioned, but I am also having difficulty.  Do you chart your cycles?  Six months really isn't that long, so try not to worry. (I know that is easier said than done) rolleyes

Good luck!


Diagnosed with UC March '07
Colazal 3 pills 3x a day
Prednisone Oct. '08 - Jan. '09
Imuran (It didn't work for me, I wrote it a Dear John letter)
Sulfasalazin 9 pills a day
Folic Acid

Regular Member

Date Joined Jul 2007
Total Posts : 163
   Posted 2/12/2009 8:20 PM (GMT -6)   
I got pregnant the first month I tried in May. I had a miscarriage at 8 weeks in July. Then we got pregnant again as soon as we started trying in October. You'll get there. Colitis can be blamed for many things, but I don't think this one. Have you tried buying an ovulation kit? Good Luck!!!!
Female,27, Diagnosed 08/2007 with extensive colitis after flaring for 10 months
Pescetarian with vegan tendencies
16 weeks pregnant 
 Medication: Lialda 4.8 mg/day 
***Offer it up to the souls in Purgatory.***

Veteran Member

Date Joined Feb 2009
Total Posts : 7150
   Posted 2/12/2009 8:58 PM (GMT -6)   
I recommended this book in another thread, but I highly recommend you get a copy of the book Taking Charge of Your Fertility and start charting. By doing so, you'll know if you're ovulating, when you're ovulating, and will be a useful tool to figure out what's wrong (if there even *is* a problem). It could just be that you're not timing things quite right!
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa nightly, Culturelle probiotic, and Zoloft (25 mg).

Forum Moderator

Date Joined Dec 2008
Total Posts : 16732
   Posted 2/12/2009 10:43 PM (GMT -6)   

I have actually read differing views about the effects of mesalamine on fertility. Most studies say there is no relation but some say fertility increases when you stop using Mesalamine. I don't know, I am on the pill and not trying to have kids - I can't offer much input.

I am curious if other people have PCOS and UC? I wonder what involvement hormones have in UC. I flared really bad after my last period and I have generally whacky hormones and I have UC. No one else in my family has this condition, I don't think it is genetic.

Diagnosed with proctitis in March 2007 - Treated with Canasa 2x Daily
Diagnosed with UC December but had symptoms months ago - Treating with Asacol (feel hopeless)

Veteran Member

Date Joined Feb 2007
Total Posts : 788
   Posted 2/12/2009 10:43 PM (GMT -6)   
It's probably not your meds, but may be your u/c.
6 months really isn't that long to try without success ( I know it feels like forever and is very very frustrating-and you probably are angry that I suggested it's not that long.....)
The first child is typically harder to conceive. Especially when you're all stressed out and putting pressure on yourself!
I kept track of my ovulating my watching my mucus production. Gross, but very interesting. Didn't help.
It wasn't until we weren't trying that we finally got pregnant. We had tried for 5 months. But 4 months later, when we weren't trying, I got pregnant.
I heard acupuncture can help with conceiving. Maybe it relaxes you enough, I don't know. You could try that.
28 yrs. old. married with one beautiful daughter (born 11/20/07)
-diagnosed with severe pancolitis u/c 2002 had total colectomy 12/19/08; emergency surgery due to abscess-had to redo ileostomy and switch to left side 12/25/08; 1/29/09 found blood clot in superior mesenteric vein (prob. from inf. and surgery inflammation)
pred. taper, coumadin, carafate, prenatal vit., and pain meds
(ileostomy temporary....not so sure?)

"Things turn out the best for those who make the best of the way things turn out."

Regular Member

Date Joined Dec 2008
Total Posts : 254
   Posted 2/13/2009 1:13 PM (GMT -6)   
We were very fortunate and got pregnant on our first try, and I'm due 3/10. However, I attribute it to the fact that I bought ovulation predictors. If I had gone by the standard cycle of a typical woman, we'd still be trying.
33 yr old female
Diagnosed with Pancolitis in 1/2007
Baby due 3/2009
Meds:1600 mg Asacol a day, Ferrex, Pre-Natal Vitamins, Lovenox, on and off Prednisone (40 mg then taper)

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