Congratulations on your pregnancy!
I'm 36 weeks pregnant. I have been taking 8 per day the whole time and personally Asacol has been the least of my concerns medication wise. I was also on 25 mg of 6MP the first trimester and have been on 40mg of Prednisone twice so far because of flare ups, once in the first and once in the second trimesters.
Asacol is a Category B drug which means: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester. It is discussed on the Asacol website: http://www.asacol.com/pdf/us-asacol.pdf
Prednisone is Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. My doctor told me the biggest concern with Prednisone is there are studies loosely correlating it to cleft palates (which develops in the earlier part of your pregnancy not the 3rd trimester). Did some internet research on it myself as well. From what we can tell on the ultrasounds - we have lucked out thank goodness.
So, is 12 right because "that's what everyone else takes?" I have no idea. But if I had to choose between taking more Asacol to lower the risk of a flareup, which means prednisone for me, I'd do it. However, I tend to flare every 4 months like clockwork and knew I was bound to get a flare while pregnant.
33 yr old female
Diagnosed with Pancolitis in 1/2007
Baby due 3/2009
Meds:1600 mg Asacol a day, Ferrex, Pre-Natal Vitamins, Lovenox, on and off Prednisone (40 mg then taper)