I was off it for about
a week, same reason, thought I had more, then Rx needed renewed, mail order wait...
I noticed a little more D, but no urgency and it wasn't bad enough to seek out the doc for samples or a small scrip to pick up locally while I waited.
The prednisone is quite likely affecting your sleep, which makes you notice your aches and pains at night more, is my guess. I hope you feel better soon.
49 year old female attorney, diagnosed UC/pancolitis 1985, no surgery but much suffering.
Asacol/5ASA 6x400 mg maintenance for 20+ years; use prednisone & Rowasa for flares.
August 2008 sought care of naturopathic doctor. Food sensitivity test showed wheat/gluten, other intolerances; started diet without gluten, soy, dairy, tomato etc. Probiotics (Ultimate Flora, 50 billion). Doing much better, but still having some bad days.