Oh, that wonder drug we love to hate. So far I don't hate it but sure someday I will - like most everyone else who goes on it. Took me about 3 days - after trying every mesalamine, suppository, enema, etc. etc. in the world - to stop the bleeding. Have not seen blood since Feb. 2 and now tapered to 20 mg. for 10 days - no problem. How can you NOT like it at this point. My doctor, of course, told me he would taper me to as low as possible without the symptoms and add 6 MP (on 6th day of that). Too bad some of us can't find something LIKE prednisone to take the rest of our lives without all the long term problems! Hey, maybe a cure - for my great-grandchildren, I hope!